Evidence map›Paper›PMID 22090401›Full record

ArticleJournal of clinical microbiology2012

Direct maldi-tof mass spectrometry assay of blood culture broths for rapid identification of Candida species causing bloodstream infections: an observational study in two large microbiology laboratories.

Teresa Spanu, Brunella Posteraro, Barbara Fiori, Tiziana D'Inzeo, Serena Campoli, Alberto Ruggeri, Mario Tumbarello, Giulia Canu, Enrico Maria Trecarichi, Gabriella Parisi and 3 more

Abstract readComparative StudyEvaluation Study
In one paragraph

Article in Journal of clinical microbiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 70 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
70citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

70 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Performance of Short-Term Culture and Direct MALDI-TOF MS for Identification of Candida Species From Blood Cultures.APMIS : acta pathologica, microbiologica, et immunologica Scandinavica · 2025
    Article
  5. Early-Onset Candidemia in Adult Intensive Care Units.Diagnostics (Basel, Switzerland) · 2025
    Review
  6. Article
  7. Review
  8. Review
  9. Review
  10. Article
  11. Review
  12. Review
  13. Article
  14. Evaluation of Identification and Susceptibility forInternational journal of microbiology · 2021
    Article
  15. Mass Spectrometry Proteotyping-Based Detection and Identification ofFrontiers in cellular and infection microbiology · 2021
    Article
  16. Biosensors and Diagnostics for Fungal Detection.Journal of fungi (Basel, Switzerland) · 2020
    Review
  17. Article
  18. Review
  19. Article
  20. Article

10 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Teresa SpanuIstituto di Microbiologia,a Istituto di Clinica delle Malattie Infettive, Rome, Italy. tspanu@rm.unicatt.it
Brunella Posteraro
Barbara Fiori
Tiziana D'Inzeo
Serena Campoli
Alberto Ruggeri
Mario Tumbarello
Giulia Canu
Enrico Maria Trecarichi
Gabriella Parisi
Mirella Tronci
Maurizio Sanguinetti
Giovanni Fadda

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We evaluated the reliability of the Bruker Daltonik's MALDI Biotyper system in species-level identification of yeasts directly from blood culture bottles. Identification results were concordant with those of the conventional culture-based method for 95.9% of Candida albicans (187/195) and 86.5% of non-albicans Candida species (128/148). Results were available in 30 min (median), suggesting that this approach is a reliable, time-saving tool for routine identification of Candida species causing bloodstream infection.

Indexed as

BloodCandidaCandidemiaHumansMicrobiological TechniquesSensitivity and SpecificitySpectrometry, Mass, Matrix-Assisted Laser Desorption-IonizationTime Factors

Identifiers

PMID22090401
PMCPMC3256727

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.