ArticleJournal of medical toxicology : official journal of the American College of Medical Toxicology2012
Effect of herbal preparation on heavy metal (cadmium) induced antioxidant system in female Wistar rats.
Article in Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 40 citations in OpenAlex.
- Propolis mitigates histopathological alterations in the pituitary gland and reproductive system of female albino rats subjected to cadmium toxicity.Veterinary world · 2025Article
- Article
- Effects of edible bird's nest and EDTA on cadmium toxicity exposed rats' embryo production, quality, and pre- and post-embryo transfer pregnancy rates.Journal of advanced veterinary and animal research · 2024Article
- Acetovanillone augmented the cardioprotective effect of carvedilol against cadmium-induced heart injury via suppression of oxidative stress and inflammation signaling pathways.Scientific reports · 2023Article
- Antioxidant and anti-inflammatory activities of Centratherum anthelminticum (L.) Kuntze seed oil in diabetic nephropathy via modulation of Nrf-2/HO-1 and NF-κB pathway.BMC complementary medicine and therapies · 2022Article
- Edible bird's nest protects histomorphology of rat's uterus against cadmium (Cd) toxicity through a reduction of Cd deposition and enhanced antioxidant activity.Saudi journal of biological sciences · 2021Article
- Characterization of functional sweetened condensed milk formulated with flavoring and sugar substitute.Food science & nutrition · 2021Article
- Urinary cadmium concentrations and risk of primary ovarian insufficiency in women: a case-control study.Environmental geochemistry and health · 2021Article
- Protective effect of Tualang honey against cadmium-induced morphological abnormalities and oxidative stress in the ovary of rats.BMC complementary medicine and therapies · 2020Article
- Article
- Cardioprotective and Antioxidant Influence of Aqueous Extracts from Sesamum indicum Seeds on Oxidative Stress Induced by Cadmium in Wistar Rats.Pharmacognosy magazine · 2016Article
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cadmium is one of the elements found to damage antioxidant systems in mammals. To ameliorate cadmium toxicity and to prevent oxidative stress, natural products may be useful. In Indian ethnobotanical practice, a mixture of 17 herbal products is used to fortify the reproductive system of women after parturition and to reverse ovarian oxidative stress. Oral administration of this extract to rats exposed to cadmium was useful in reversing oxidative stress. Two different doses of cadmium (50 ppm and 200 ppm) were given to Wistar rats aged 45 and 65 days. An herbal extract derived from 17 plants was administered orally every day at a dose level of 200 mg/kg of body weight to the rats exposed to cadmium. A battery of enzymes involved in antioxidant activity in the ovary, including superoxide dismutase (SOD), catalase, glutathione peroxidase (GPx) and glutathione-s-transferase (GST) were measured in the control, cadmium-exposed rats without treatment and in the cadmium-exposed rats treated with herbal extract. The reduction in SOD, catalase, GPx and GST activity after cadmium exposure improved significantly in the rats treated with the herbal extract (p < 0.05). The decrease of antioxidant enzymes due to cadmium exposure was reversed significantly with herbal extract administration. The synergistic effect of each bioactive compound in different herbal extracts requires further study.
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