Evidence map›Paper›PMID 22090090›Full record

ArticleDer Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft2011

[Therapy options for chronic central serous chorioretinopathy. Photodynamic therapy combined with bevacizumab - a case series].

M Maier, V Valet, N Feucht, C P Lohmann

Abstract readCase ReportsEnglish Abstract
PubMed Publisher
In one paragraph

Article in Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. [Mineralocorticoid receptor antagonists as treatment option for acute and chronic central serous chorioretinopathy].Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft · 2014
    Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

M MaierKlinik und Poliklinik für Augenheilkunde, Klinikum rechts der Isar der Technischen Universität München, München, Deutschland. Mathias.Maier@mri.tum.de
V Valet
N Feucht
C P Lohmann
Klinikum rechts der Isar · DEKlinik und Poliklinik für Augenheilkunde Universitätsklinikum Regensburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis article reports about the use of a combined photodynamic therapy (PDT) and intravitreal injection of bevacizumab as a treatment option in nine patients with chronic central serous chorioretinopathy (CSC). PATIENTS AND

methodsA total of nine male patients with chronic CSC were treated with standard PDT laser treatment with verteporfin and intravitreal injection of bevacizumab administered within 24 h. Before and 1, 3, 6, 9 and 12 months after treatment the results of visual acuity, fluorescein angiography (FA) and optical coherence tomography (OCT) examinations were documented.

resultsAll patients showed an improvement in visual acuity of 1-4 ETDRS lines. Mean visual acuity increased from baseline 20 / 40 to 20 / 25 after 3 months. FA and OCT findings showed a restitution of leakages and subretinal fluid in all cases. After 6-12 months follow-up 8 patients had ongoing improvement in vision without recurrence of CSC.

conclusionThe combination of PDT with bevacizumab in this case series appears to be an effective and safe therapy combination which is suitable as a therapeutic option for patients with chronic CCS without a tendency to recovery.

Indexed as

AdultAngiogenesis InhibitorsAntibodies, Monoclonal, HumanizedBevacizumabCentral Serous ChorioretinopathyCombined Modality TherapyHumansMaleMiddle AgedPhotochemotherapyTreatment OutcomeAngiogenesis InhibitorsAntibodies, Monoclonal, HumanizedBevacizumab

Identifiers

PMID22090090
OpenAlexW2239713553

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.