Evidence map›Paper›PMID 22090029›Full record

ReviewThe Journal of biological chemistry2012

Packaging of fat: an evolving model of lipid droplet assembly and expansion.

Dawn L Brasaemle, Nathan E Wolins

Abstract readReview
In one paragraph

Review in The Journal of biological chemistry, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 108 papers.

0numbers the graph read from it
0cells of the map it votes in
108citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

108 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Pathophysiology of Lipid Droplets in Neuroglia.Antioxidants (Basel, Switzerland) · 2021
    Review
  17. Review
  18. Article
  19. Review
  20. Biogenesis and Breakdown of Lipid Droplets in Pathological Conditions.Frontiers in cell and developmental biology · 2021
    Review

48 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Dawn L BrasaemleRutgers Center for Lipid Research and Department of Nutritional Sciences, Rutgers, The State University of New Jersey, New Brunswick, New Jersey 08901, USA. brasaemle@aesop.rutgers.edu
Nathan E Wolins

Funding

PERILIPINS AND CELLULAR TRIACYLGLYCEROL METABOLISMR01DK054797 · NIDDK · RUTGERS THE ST UNIV OF NJ NEW BRUNSWICK · PI BRASAEMLE, DAWN L · 2000 to 2014
$3.9M
THE ROLE OF OXPAT IN FAT TRAFFICKING AND SKELETAL MUSCLE METABOLISMR01DK088206 · NIDDK · WASHINGTON UNIVERSITY · PI WOLINS, NATHAN E · 2011 to 2015
$1.7M
NIDDK NIH HHS DK054797NIDDK NIH HHS DK088206NIDDK NIH HHS R01 DK054797NIDDK NIH HHS R01 DK088206
6 · The paper itself

Abstract

Lipid droplets (LDs) are organelles found in most types of cells in the tissues of vertebrates, invertebrates, and plants, as well as in bacteria and yeast. They differ from other organelles in binding a unique complement of proteins and lacking an aqueous core but share aspects of protein trafficking with secretory membrane compartments. In this minireview, we focus on recent evidence supporting an endoplasmic reticulum origin for LD formation and discuss recent findings regarding LD maturation and fusion.

Indexed as

AnimalsBacteriaEndoplasmic ReticulumHumansLipid MetabolismPlantsYeasts

Identifiers

PMID22090029
PMCPMC3268387

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.