ReviewThe Indian journal of medical research2011
Past, present & future scenario of thalassaemic care & control in India.
Review in The Indian journal of medical research, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
38 citing papers in PubMed, 65 citations in OpenAlex.
- Experience of Prenatal Diagnosis for β-Thalassemia and Major Hemoglobinopathies in the Last Decade from Seven Tertiary-Care Referral Centers in India.Indian journal of pediatrics · 2026Article
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- Prenatal hemoglobinopathy screening & prevention in India: A cross-sectional study.The Indian journal of medical research · 2025Article
- A Comprehensive Gap Analysis of Risk Factors for Transfusion Dependent Thalassemia in Siblings.Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion · 2025Article
- Experience of Antenatal Thalassemia Screening and Prenatal Diagnosis from a Tertiary Care Teaching Hospital in Punjab.Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion · 2025Article
- The Neonatal Screening for Sickle Cell Disease, Thalassemia, and G6PD Deficiency in Central India.Journal of pharmacy & bioallied sciences · 2024Article
- Comprehensive Neonatal Screening for Genetic Disorders in Tribal Populations of Central India.Journal of pharmacy & bioallied sciences · 2024Article
- Awareness and practical evaluation of correct use of iron chelators; a study to track the ambiguities of thalassemia patients on their medications in Iran.BMC research notes · 2024Article
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- Thalassemia, biobanking infrastructures, and personalized stem cell therapies in Chennai.Frontiers in sociology · 2023Article
- Article
- Use of rapid cardiac magnetic resonance imaging to guide chelation therapy in patients with transfusion-dependent thalassaemia in India: UMIMI study.European heart journal. Quality of care & clinical outcomes · 2022Article
- Performance of second-trimester maternal biochemistry screening (quadruple testThe Indian journal of medical research · 2021Observational
- Vitamins in Cereals: A Critical Review of Content, Health Effects, Processing Losses, Bioaccessibility, Fortification, and Biofortification Strategies for Their Improvement.Frontiers in nutrition · 2021Review
- Utility of screening tools to differentiate beta thalassemia trait and iron-deficiency anemia - do they serve a purpose in blood donors?Blood research · 2020Article
- Evaluation of Factors Affecting Awareness About Beta-Thalassemia in Western Rajasthan.Journal of family medicine and primary care · 2020Article
- Life expectancy and risk factors for early death in patients with severe thalassemia syndromes in South India.Blood advances · 2020Article
- Need for a universal thalassemia screening programme in India? A public health perspective.Journal of family medicine and primary care · 2019Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The first case of thalassaemia, described in a non-Mediterranean person, was from India. Subsequently, cases of thalassaemia were documented in all parts of India. Centres for care of thalassaemics were started in the mid-1970s in Mumbai and Delhi, and then in other cities. The parent's associations, with the help of International Thalassemia Federation, greatly helped in improving the care of thalassaemics. Obtaining blood for transfusion was difficult, but the Indian Red Cross Society and the parent's associations played a crucial role in arranging voluntary donations of blood. Chelation with deferoxamine was used sparingly due to the high cost. The Indian physicians conducted trials with deferiprone, and the drug was first approved and marketed in India. Deferasirox is also now being administered. Studies of physical and pubertal growth documented significant retardation, suggesting that generally patients receive inadequate chelation and transfusions. Bone marrow transplantation is available at a number of centres, and cord blood stem cell storage facilities have been established. Information about mutations in different parts of India is available, and ThalInd, an Indian database has been set up. There is a need to set up preimplantation genetic diagnosis and non-invasive prenatal diagnosis. It is argued that too much emphasis should not be placed on premarital screening. The focus should be on screening pregnant women to yield immediate results in reducing the burden of this disorder. Care of thalassaemia has been included in the 12 th 5-year Plan of the Government of India. Many States now provide blood transfusions and chelation free of cost. Although inadequacies in care of thalassaemia remain, but the outlook is bright, and the stage is set for initiating a control programme in the high risk States.
Indexed as
Identifiers
22089615PMC3237251W2077361697What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.