ArticleJournal of assisted reproduction and genetics2011
Maturation outcomes are improved following Cryoleaf vitrification of immature human oocytes when compared to choline-based slow-freezing.
Article in Journal of assisted reproduction and genetics, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
9 citing papers in PubMed.
- Bisphenol-A and human oocyte maturation in vitro.Human reproduction (Oxford, England) · 2013Trial
- Cryopreservation of Mammalian Oocytes: Slow Cooling and Vitrification Approaches.Methods in molecular biology (Clifton, N.J.) · 2026Article
- C-phycocyanin improves the developmental potential of cryopreserved human oocytes by minimizing ROS production and cell apoptosis.PloS one · 2024Article
- Cryopreservation of Mammalian Oocytes: Slow Cooling and Vitrification as Successful Methods for Cryogenic Storage.Methods in molecular biology (Clifton, N.J.) · 2021Article
- Fertility preservation for trans men: frozen-thawed in vitro matured oocytes collected at the time of ovarian tissue processing exhibit normal meiotic spindles.Journal of assisted reproduction and genetics · 2017Article
- In vitro maturation of human immature oocytes for fertility preservation and research material.Reproductive medicine and biology · 2017Review
- Female fertility: is it safe to "freeze?".Chinese medical journal · 2015Review
- Evaluation of the impact of vitrification on the actin cytoskeleton of in vitro matured ovine oocytes by means of Raman microspectroscopy.Journal of assisted reproduction and genetics · 2015Article
- Ultrastructure of human mature oocytes after vitrification.European journal of histochemistry : EJH · 2012Review
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe cryopreservation of immature oocytes permits oocyte banking for patients at risk of losing their fertility. However, the optimum protocol for such fertility preservation remains uncertain.
methodsThe present study investigated the survival, maturation, cytoskeletal and chromosome organization of sibling immature oocytes leftover from controlled ovarian stimulation cycles, that were either slow-frozen (with choline-substitution) or vitrified. A comparison group included oocytes that were never cryopreserved.
resultsAmong the three groups, comparable rates were observed for both survival (67-70%) and polar body extrusion (59-79%). Significantly more oocytes underwent spontaneous activation after IVM following slow-freezing compared with either vitrification or no cryopreservation. Likewise, the incidence of spindle abnormalities was greatest in the slow-frozen group, with no differences in spindle morphometrics or chromosome organization.
conclusionsWhile the overall incidence of mature oocytes with normal bipolar spindles from warmed immature oocytes was low, the yield using Cryoleaf vitrification was slightly superior to choline-based slow-freezing.
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Registered trials
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