ArticleHippokratia2006
Hypomagnesemia and cardiovascular system.
Article in Hippokratia, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 52 citations in OpenAlex.
- Per-Protocol Analysis of Chlorthalidone Versus Hydrochlorothiazide for Cardiovascular Event Prevention-Diuretic Comparison Project.Journal of the American Heart Association · 2026Trial
- Comparative Efficacy of Magnesium and Potassium Towards Cholesterol and Quality of Life in Patients With Type 2 Diabetes Mellitus: A Randomised Single-Blinded Controlled Clinical Trial.Endocrinology, diabetes & metabolism · 2024Trial
- Electrolyte and mineral disturbances in septic acute kidney injury patients undergoing continuous renal replacement therapy.Medicine · 2016Trial
- Magnesium and Cardiac Arrythmias: An Overlooked Guardian of Electrical Stability.Cardiology research · 2026Review
- Omeprazole and Risk of Hypertension: Analysis of Existing Literature and the WHO Global Pharmacovigilance Database.Drugs - real world outcomes · 2024Article
- The Significance of Low Magnesium Levels in COVID-19 Patients.Medicina (Kaunas, Lithuania) · 2023Review
- Clinician preference instrumental variable analysis of the effectiveness of magnesium supplementation for atrial fibrillation prophylaxis in critical care.Scientific reports · 2022Observational
- Arrhythmic triad in an implantable cardioverter-defibrillator recipient with severe hypokalemia.Journal of arrhythmia · 2022Article
- The Role of Hypomagnesemia in Cardiac Arrhythmias: A Clinical Perspective.Biomedicines · 2022Review
- A study of serum magnesium levels in postoperative ICU patients undergoing major GI surgeries.Medical journal, Armed Forces India · 2022Article
- Ventricular Arrhythmia Associated With Magnesium and Vitamin D Deficiencies in a Patient With Rheumatoid Arthritis.Cureus · 2021Article
- An overview of diagnosis and management of drug-induced hypomagnesemia.Pharmacology research & perspectives · 2021Review
- Magnesium, Little Known But Possibly Relevant: A Link between NASH and Related Comorbidities.Biomedicines · 2021Review
- Hospital-Acquired Dysmagnesemia and In-Hospital Mortality.Medical sciences (Basel, Switzerland) · 2020Article
- Reduced Plasma Magnesium Levels in Type-1 Diabetes Associate with Prothrombotic Changes in Fibrin Clotting and Fibrinolysis.Thrombosis and haemostasis · 2020Article
- Coagulatory Defects in Type-1 and Type-2 Diabetes.International journal of molecular sciences · 2019Review
- Magnesium: The Forgotten Electrolyte-A Review on Hypomagnesemia.Medical sciences (Basel, Switzerland) · 2019Review
- Drug-physiology interaction and its influence on the QT prolongation-mechanistic modeling study.Journal of pharmacokinetics and pharmacodynamics · 2018Article
- Magnesium and Human Health: Perspectives and Research Directions.International journal of endocrinology · 2018Review
- Cardiac Dysrhythmias and Neurological Dysregulation: Manifestations of Profound Hypomagnesemia.Case reports in cardiology · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Magnesium depletion in clinical practice is mainly related to loop diuretics and thiazides. Among patients treated with diuretics more than 1/3 exhibit hypomagnesa. Arrhythmias and sudden death attributed to magnesium depletion could be prevented by Mg administration. Magnesium deficiency in experimental animals promotes atherosclerotic lesions whereas this ion is involved in various stages of myocardial damage after experimental coronary artery occlusion. In humans magnesium administration in the first 24 hours of myocardial infarction was related to beneficial effects in first year mortality rate. Nevertheless more evidence from clinical investigation is needed for permanent conclutions.
Indexed as
Identifiers
22087052PMC2464251W150192644What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.