ReviewHeart failure reviews2012
The cardiorenal syndrome in heart failure: cardiac? renal? syndrome?
Review in Heart failure reviews, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 28 citations in OpenAlex.
- Hypertensive Heart Failure.Journal of clinical medicine · 2023Review
- Obesity, inflammation, and heart failure: links and misconceptions.Heart failure reviews · 2022Review
- The Pathogenesis of End-Stage Renal Disease from the Standpoint of the Theory of General Pathological Processes of Inflammation.International journal of molecular sciences · 2021Review
- Red blood cell distribution width in elderly hospitalized patients with cardiovascular disease.World journal of cardiology · 2021Article
- Insights of Worsening Renal Function in Type 1 Cardiorenal Syndrome: From the Pathogenesis, Biomarkers to Treatment.Frontiers in cardiovascular medicine · 2021Review
- Relationship of High Circulating Cystatin C to Biochemical Markers of Bone Turnover and Bone Mineral Density in Elderly Males with a Chronic Heart Failure.Journal of medical biochemistry · 2019Article
- Response and outcomes of cardiac resynchronization therapy in patients with renal dysfunction.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2018Article
- Approach to hyponatremia in congestive heart failure: a survey of Canadian specialist physicians and trainees.Canadian journal of kidney health and disease · 2016Article
- Water and sodium in heart failure: a spotlight on congestion.Heart failure reviews · 2015Review
- Epidemiology and importance of renal dysfunction in heart failure patients.Current heart failure reports · 2013Review
- Current strategies for preventing renal dysfunction in patients with heart failure: a heart failure stage approach.Clinics (Sao Paulo, Brazil) · 2013Review
- Prevalence and importance of comorbidities in patients with heart failure.Current heart failure reports · 2012Review
- Heart failure 2012.Cardiology research and practice · 2012Article
- Current status of mechanical circulatory support: a systematic review.Cardiology research and practice · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
There has been increasing interest on the so-called cardiorenal syndrome (CRS), defined as a complex pathophysiological disorder of the heart and kidneys whereby acute or chronic dysfunction in one organ may induce acute or chronic dysfunction in the other. In this review, we contend that there is lack of evidence warranting the adoption of a specific clinical construct such as the CRS within the heart failure (HF) syndrome by demonstrating that: (a) the approaches and tools regarding the definition of kidney involvement in HF are suboptimal; (b) development of renal failure in HF is often confounded by age, hypertension, and diabetes; (c) worsening of renal function (WRF) in HF may be largely independent of alterations in cardiac function; (d) the bidirectional association between HF and renal failure is not unique and represents one of the several such associations encountered in HF; and (e) inflammation is a common denominator for HF and associated noncardiac morbidities. Based on these arguments, we believe that dissecting one of the multiple bidirectional associations in HF and constructing the so-called cardiorenal syndrome is not justified pathophysiologically. Fully understanding of all morbid associations and not only the cardiorenal is of great significance for the clinician who is caring for the patient with HF.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.