ArticlePsychological medicine2012
Is maternal smoking during pregnancy a causal environmental risk factor for adolescent antisocial behavior? Testing etiological theories and assumptions.
Article in Psychological medicine, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 53 citations in OpenAlex.
- Patterns of adverse childhood experiences and associations with prenatal substance use and poor infant outcomes in a multi-country cohort of mothers: a latent class analysis.BMC pregnancy and childbirth · 2022Article
- Developmental effects of maternal smoking during pregnancy on the human frontal cortex transcriptome.Molecular psychiatry · 2020Article
- Using a cross-cohort comparison design to test the role of maternal smoking in pregnancy in child mental health and learning: evidence from two UK cohorts born four decades apart.International journal of epidemiology · 2020Article
- Maternal smoking during pregnancy and offspring personality in childhood and adulthood.Journal of personality · 2018Article
- Does MAOA increase susceptibility to prenatal stress in young children?Neurotoxicology and teratology · 2017Article
- Microsatellite polymorphisms associated with human behavioural and psychological phenotypes including a gene-environment interaction.BMC medical genetics · 2017Article
- Interacting effect of MAOA genotype and maternal prenatal smoking on aggressive behavior in young adulthood.Journal of neural transmission (Vienna, Austria : 1996) · 2016Article
- Epidemiology of child psychopathology: major milestones.European child & adolescent psychiatry · 2015Review
- Prenatal tobacco exposure and self-regulation in early childhood: Implications for developmental psychopathology.Development and psychopathology · 2015Article
- Is maternal smoking during pregnancy associated with bipolar disorder in offspring?Journal of affective disorders · 2015Article
- Prenatal nicotine exposure and child behavioural problems.European child & adolescent psychiatry · 2014Review
- A sibling-comparison study of smoking during pregnancy and childhood psychological traits.Behavior genetics · 2014Article
- Prenatal glucocorticoids and maternal smoking during pregnancy independently program adult nicotine dependence in daughters: a 40-year prospective study.Biological psychiatry · 2014Article
- Maternal smoking during pregnancy and bipolar disorder in offspring.The American journal of psychiatry · 2013Article
- Commentary: gene by environment interplay and psychopathology--in search of a paradigm.Journal of child psychology and psychiatry, and allied disciplines · 2013Article
- Critical need for family-based, quasi-experimental designs in integrating genetic and social science research.American journal of public health · 2013Article
- Article
- Familial confounding of the association between maternal smoking during pregnancy and offspring substance use and problems.Archives of general psychiatry · 2012Article
- Impact of prenatal exposure characterization on early risk detection: Methodologic insights for the HEALthy Brain and Child Development (HBCD) study.Neurotoxicology and teratologyArticle
- Tobacco exposure and maternal psychopathology: Impact on toddler problem behavior.Neurotoxicology and teratologyArticle
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Authors and funding
5 authors at 4 institutions in 1 country.
Funding
Abstract
backgroundAlthough many studies indicate that maternal smoking during pregnancy (SDP) is correlated with later offspring antisocial behavior (ASB), recent quasi-experimental studies suggest that background familial factors confound the association. The present study sought to test alternative etiological hypotheses using multiple indices of adolescent ASB, comparing differentially exposed siblings, and testing assumptions in the sibling-comparison design.
methodThe study examined the association between maternal SDP and adolescent-reported ASB, criminal convictions and membership in a group of individuals with early-starting and chronic ASB among 6066 offspring of women from the National Longitudinal Survey of Youth, a representative sample of women in the USA. The analyses controlled for statistical covariates and examined associations while comparing differentially exposed siblings.
resultsAt the population level, each additional pack of cigarettes per day predicted greater mean adolescent-reported ASB symptoms [ratio of means 1.15, 95% confidence interval (CI) 1.08-1.22], odds of being in the top 10% of ASB [odds ratio (OR) 1.34, 95% CI 1.10-1.65], hazard of a criminal conviction [hazard ratio (HR) 1.51, 95% CI 1.34-1.68] and odds of chronic ASB (OR 1.57, 95% CI 1.25-1.99). SDP robustly predicted most assessments of ASB while controlling for measured covariates. When siblings exposed to differing levels of SDP were compared, however, all of the associations were attenuated and were not statistically significant: adolescent-reported mean ASB (ratio of means 0.86, 95% CI 0.74-1.01), high ASB (OR 0.67, 95% CI 0.41-1.12), criminal conviction (HR 0.98, 95% CI 0.66-1.44) and chronic ASB (OR 0.80, 95% CI 0.46-1.38).
conclusionsThe results strongly suggest that familial factors account for the correlation between SDP and offspring adolescent ASB, rather than a putative causal environmental influence of SDP.
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