Trial reportCulture, health & sexuality2012
Variations in microbicide gel acceptability among young women in the USA and Puerto Rico.
Trial report in Culture, health & sexuality, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 32 citations in OpenAlex.
- Factors Supporting and Hindering Adherence to Rectal Microbicide Gel Use with Receptive Anal Intercourse in a Phase 2 Trial.AIDS and behavior · 2018Trial
- Soluble Immune Mediators and Vaginal Bacteria Impact Innate Genital Mucosal Antimicrobial Activity in Young Women.American journal of reproductive immunology (New York, N.Y. : 1989) · 2015Trial
- Trial
- User acceptability profiles of vaginal treatments among women with genitourinary syndrome of menopause.PloS one · 2025Article
- Multipurpose Prevention Technologies: Oral, Parenteral, and Vaginal Dosage Forms for Prevention of HIV/STIs and Unplanned Pregnancy.Polymers · 2021Review
- Developing a culturally appropriate illustrated tool for the self-collection of anorectal specimens for the testing of sexually transmitted infections: lessons from Papua New Guinea.BMC public health · 2019Article
- Qualitative exploration of intrinsic and extrinsic factors that influence acceptability of semisoft vaginal suppositories.BMC women's health · 2018Article
- Article
- On-demand microbicide products: design matters.Drug delivery and translational research · 2017Review
- Lessons for Rectal Microbicide Development From an Acceptability Trial of a Placebo Gel Applied Prior to Receptive Anal Intercourse.Archives of sexual behavior · 2017Article
- Innovative sensory methods to access acceptability of mixed polymer semisoft ovules for microbicide applications.Drug delivery and translational research · 2016Article
- Drivers of Vaginal Drug Delivery System Acceptability from Internet-Based Conjoint Analysis.PloS one · 2016Article
- Firmness Perception Influences Women's Preferences for Vaginal Suppositories.Pharmaceutics · 2014Article
- Attitudes towards microbicide use for bacterial vaginosis in pregnancy.Sexual health · 2014Article
- Release of tenofovir from carrageenan-based vaginal suppositories.Pharmaceutics · 2014Article
- Topical microbicides and HIV prevention in the female genital tract.Journal of clinical pharmacology · 2014Review
- Article
- Young women's experience with using videoconferencing for the assessment of sexual behavior and microbicide use.Telemedicine journal and e-health : the official journal of the American Telemedicine Association · 2013Article
- Young adult women and correlates of potential adoption of pre-exposure prophylaxis (PrEP): results of a national survey.Current HIV research · 2013Article
- The Motivations and Experiences of Young Women in a Microbicide Trial in the USA and Puerto Rico.World journal of AIDS · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 7 institutions in 1 country.
Funding
Abstract
In a multi-site study of vaginal microbicide acceptability conducted with sexually active young women, quantitative assessments revealed significant differences in acceptability by site. Participants in Puerto Rico rated the gel more favourably than mainland US participants in terms of liking the gel and likelihood of future use. To explain these differences, we examined responses to qualitative behavioural assessments. Young women in mainland USA associated gel leakage with uncomfortable sensations experienced during menstruation, while young women in Puerto Rico had positive associations of gel use with douching. These negative or positive associations affected assessments of the gel's physical qualities. In addition, young women's perceptions of primary partners' support for microbicide use influenced sexual satisfaction with the gel and, ultimately, product acceptability. Finally, geographic HIV-risk context contributed to heightened HIV-risk perception, which influenced likelihood of future microbicide use, even for women in stated monogamous relationships. Future microbicide acceptability studies should take into account potential differences in acceptability by site such as HIV-risk perception based on local HIV prevalence, popularity of vaginal hygiene products in a specific area and male attitudes in different cultures concerning women's use of HIV protection strategies.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.