ArticleThrombosis2011
Deep vein thrombosis prophylaxis in trauma patients.
Article in Thrombosis, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
43 citing papers in PubMed, 3 syntheses or guidelines pooled it, 122 citations in OpenAlex.
- Tranexamic acid in trauma: A joint position statement and resource document of NAEMSP, ACEP, and ACS-COT.The journal of trauma and acute care surgery · 2025Guideline
- Prevalence of preoperative deep vein thrombosis in long bone fractures of lower limbs: a systematic review and meta-analysis.Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology · 2023Pooled it
- The use of direct oral anticoagulants for extended duration thromboprophylaxis in medically ill patients: a systematic review and meta-analysis.Journal of thrombosis and thrombolysis · 2019Pooled it
- Postinjury hyperfibrinogenemia compromises efficacy of heparin-based venous thromboembolism prophylaxis.Shock (Augusta, Ga.) · 2014Trial
- Platelets are dominant contributors to hypercoagulability after injury.The journal of trauma and acute care surgery · 2013Trial
- Risk factors for vascular occlusive events and death due to bleeding in trauma patients; an analysis of the CRASH-2 cohort.PloS one · 2012Trial
- Integrating Peripheral Nerve Blocks in Multiple Trauma Care: Current Evidence and Clinical Challenges.Journal of clinical medicine · 2025Review
- Rapid Thromboelastography Identifies Coagulopathy and Predicts Poor Outcomes in Severe Traumatic Brain Injury.Cureus · 2025Article
- "A prospective study on the effectiveness of monoprophylaxis with aspirin to prevent thromboembolism in total knee arthroplasty patients".Journal of orthopaedics · 2025Article
- Traumatic spine fractures and concomitant venous thromboembolism: A systematic review.World neurosurgery: X · 2024Review
- Integrated landscape of plasma metabolism and proteome of patients with post-traumatic deep vein thrombosis.Nature communications · 2024Article
- Complications of Venous Thromboembolism Chemoprophylaxis in Lumbar Laminectomy With and Without Fusion.International journal of spine surgery · 2024Article
- Popliteal Artery-Related Pathologies in Athletes-A Primer for Musculoskeletal Radiologists.The Indian journal of radiology & imaging · 2024Review
- Article
- Venous thromboembolism in orthopedic surgery: Global guidelines.Acta orthopaedica et traumatologica turcica · 2023Review
- Article
- Haemostasis and Inflammatory Parameters as Potential Diagnostic Biomarkers for VTE in Trauma-Immobilized Patients.Diagnostics (Basel, Switzerland) · 2023Review
- The prediction of mortality influential variables in an intensive care unit: a case study.Personal and ubiquitous computing · 2023Article
- Study of Deep Vein Thrombosis Screening by using Ultrasound Doppler in Patients with Pelvic and Acetabulum Fractures Requiring Operative Intervention.Malaysian orthopaedic journal · 2022Article
- Physiological parameters and the use of compression stockings in individuals with spinal cord injuries: a scoping review.Spinal cord · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Deep vein thrombosis (DVT) and pulmonary embolism (PE) are known collectively as venous thromboembolism (VTE). Venous thromboembolic events are common and potentially life-threatening complications following trauma with an incidence of 5 to 63%. DVT prophylaxis is essential in the management of trauma patients. Currently, the optimal VTE prophylaxis strategy for trauma patients is unknown. Traditionally, pelvic and lower extremity fractures, head injury, and prolonged immobilization have been considered risk factors for VTE; however it is unclear which combination of risk factors defines a high-risk group. Modalities available for trauma patient thromboprophylaxis are classified into pharmacologic anticoagulation, mechanical prophylaxis, and inferior vena cava (IVC) filters. The available pharmacologic agents include low-dose heparin (LDH), low molecular weight heparin (LMWH), and factor Xa inhibitors. Mechanical prophylaxis methods include graduated compression stockings (GCSs), pneumatic compression devices (PCDs), and A-V foot pumps. IVCs are traditionally used in high risk patients in whom pharmacological prophylaxis is contraindicated. Both EAST and ACCP guidelines recommend primary use of LMWHs in trauma patients; however there are still controversies regarding the definitive VTE prophylaxis in trauma patients. Large randomized prospective clinical studies would be required to provide level I evidence to define the optimal VTE prophylaxis in trauma patients.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.