ReviewGenetics2011
Yeast: an experimental organism for 21st Century biology.
Review in Genetics, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 246 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
246 citing papers in PubMed.
- Reduced Schiff Base Copper(II) Complexes Derived from 2-, 3-, and 4-Methoxybenzylamine: DNA Binding and Cleavage, BSA Binding, Cytotoxic and SOD Mimetic Properties.International journal of molecular sciences · 2026Article
- The genetics of the many forms of diversity.Genetics · 2026Article
- Article
- Protocol for mapping gene essentiality changes in yeast using inducible gene deletion mutants.STAR protocols · 2026Article
- Horizontal gene transfer in Saccharomyces cerevisiae and other Saccharomycotina yeasts: a review.World journal of microbiology & biotechnology · 2026Review
- Lipidomic Insight Across 48Microorganisms · 2026Article
- Yeast as a Model for Human Disease.International journal of molecular sciences · 2026Review
- Extremophilic Yeasts as Next-Generation Eukaryotic Models: Mechanisms of Stress Integration, Systems Biology and Biotechnological Applications: A Review.Journal of fungi (Basel, Switzerland) · 2026Review
- Systems biology of yeast metabolism.FEMS yeast research · 2026Review
- From one genome to thousands, and beyond.FEMS yeast research · 2026Review
- Article
- The Power of Yeast.Yeast (Chichester, England) · 2025Review
- Assembly and delivery of large DNA via chromosome elimination in yeast.Nature protocols · 2025Review
- Genetic properties of mercury‑tolerant yeast, Pichia kudriavzevii 1P4.International microbiology : the official journal of the Spanish Society for Microbiology · 2025Article
- Special Issue: "Yeast as a Model System to Study Human Diseases".International journal of molecular sciences · 2025Article
- Barcode sequencing: a robust, platform-agnostic method for massively parallel cell-based screens.G3 (Bethesda, Md.) · 2025Article
- Synthesis, Structure, DNA/BSA Binding, DNA Cleaving, Cytotoxic and SOD Mimetic Activities of Copper(II) Complexes Derived from Methoxybenzylamine Schiff Base Ligands.Molecules (Basel, Switzerland) · 2025Article
- Yeast adapts to diverse ecological niches driven by genomics and metabolic reprogramming.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Plants, fungi, and antifungals: A little less talk, a little more action.PLoS pathogens · 2025Article
- Generating combinatorial diversity via engineered V(D)J-like recombination in Saccharomyces cerevisiae.Nature communications · 2025Article
186 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
In this essay, we revisit the status of yeast as a model system for biology. We first summarize important contributions of yeast to eukaryotic biology that we anticipated in 1988 in our first article on the subject. We then describe transformative developments that we did not anticipate, most of which followed the publication of the complete genomic sequence of Saccharomyces cerevisiae in 1996. In the intervening 23 years it appears to us that yeast has graduated from a position as the premier model for eukaryotic cell biology to become the pioneer organism that has facilitated the establishment of the entirely new fields of study called "functional genomics" and "systems biology." These new fields look beyond the functions of individual genes and proteins, focusing on how these interact and work together to determine the properties of living cells and organisms.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.