ReviewDevelopmental dynamics : an official publication of the American Association of Anatomists2012
Drosophila as a model for epithelial tube formation.
Review in Developmental dynamics : an official publication of the American Association of Anatomists, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
39 citing papers in PubMed.
- RNAseK is vital for epithelial function in Drosophila melanogaster.The Journal of experimental biology · 2026Article
- The extracellular protease AdamTS-B is a dosage-sensitive regulator of unicellular tracheal branch morphogenesis.Biology open · 2026Article
- Hemocyte-secreted papilin bearing mucin-typeiScience · 2026Article
- Viscous shear is a key force in Drosophila ventral furrow morphogenesis.Development (Cambridge, England) · 2024Article
- The Enigmas of Tissue Closure: Inspiration fromCurrent issues in molecular biology · 2024Review
- Maternally-Activated Lineage Tracing (microPublication biology · 2024Article
- Expanding the Junction: New Insights into Non-Occluding Roles for Septate Junction Proteins during Development.Journal of developmental biology · 2021Review
- Transcriptomic and Genetic Analyses Identify the Krüppel-Like Factor Dar1 as a New Regulator of Tube-Shaped Long Tendon Development.Frontiers in cell and developmental biology · 2021Article
- A Series of Tubes: TheJournal of developmental biology · 2020Review
- Aging and the clock: Perspective from flies to humans.The European journal of neuroscience · 2020Review
- Article
- Key roles of Arf small G proteins and biosynthetic trafficking for animal development.Small GTPases · 2019Review
- In developing mouse kidneys, orientation of loop of Henle growth is adaptive and guided by long-range cues from medullary collecting ducts.Journal of anatomy · 2019Article
- Role of tbc1 in Drosophila embryonic salivary glands.BMC molecular and cell biology · 2019Article
- Article
- The apical protein Apnoia interacts with Crumbs to regulate tracheal growth and inflation.PLoS genetics · 2019Article
- Tubular Excretory Canal Structure Depends on Intermediate Filaments EXC-2 and IFA-4 inGenetics · 2018Article
- Claudins in morphogenesis: Forming an epithelial tube.Tissue barriers · 2017Review
- A holey pursuit: lumen formation in the developing kidney.Pediatric nephrology (Berlin, Germany) · 2017Review
- Fold formation at the compartment boundary of Drosophila wing requires Yki signaling to suppress JNK dependent apoptosis.Scientific reports · 2016Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
Epithelial tubular organs are essential for life in higher organisms and include the pancreas and other secretory organs that function as biological factories for the synthesis and delivery of secreted enzymes, hormones, and nutrients essential for tissue homeostasis and viability. The lungs, which are necessary for gas exchange, vocalization, and maintaining blood pH, are organized as highly branched tubular epithelia. Tubular organs include arteries, veins, and lymphatics, high-speed passageways for delivery and uptake of nutrients, liquids, gases, and immune cells. The kidneys and components of the reproductive system are also epithelial tubes. Both the heart and central nervous system of many vertebrates begin as epithelial tubes. Thus, it is not surprising that defects in tube formation and maintenance underlie many human diseases. Accordingly, a thorough understanding how tubes form and are maintained is essential to developing better diagnostics and therapeutics. Among the best-characterized tubular organs are the Drosophila salivary gland and trachea, organs whose relative simplicity have allowed for in depth analysis of gene function, yielding key mechanistic insight into tube initiation, remodeling and maintenance. Here, we review our current understanding of salivary gland and trachea formation - highlighting recent discoveries into how these organs attain their final form and function.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.