ArticleGenesis (New York, N.Y. : 2000)2012
Characterization of a novel Xenopus tropicalis cell line as a model for in vitro studies.
Article in Genesis (New York, N.Y. : 2000), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 32 citations in OpenAlex.
- Genotoxic effects of association of the biogenic amines cadaverine and putrescine on the Xenopus tropicalis fibroblast cell line.Environmental science and pollution research international · 2026Article
- FISH mapping in Xenopus pygmaeus refines understanding of genomic rearrangements and reveals jumping NORs in African clawed frogs.Heredity · 2025Article
- Consequences of polyploidy and divergence as revealed by cytogenetic mapping of tandem repeats in African clawed frogs (European journal of wildlife research · 2023Article
- Developing immortal cell lines fromOpen biology · 2022Article
- Article
- Construction of Whole Genomes from Scaffolds Using Single Cell Strand-Seq Data.International journal of molecular sciences · 2021Article
- Establishing Cell Lines from Fresh or Cryopreserved Tissue from the Great Crested Newt (Animals : an open access journal from MDPI · 2021Article
- Evolutionary Dynamics of the Repetitive DNA in the Karyotypes ofFrontiers in genetics · 2020Article
- Karyomaps of cultured and cryobankedData in brief · 2018Article
- Article
- Article
- Mariner Transposons Contain a Silencer: Possible Role of the Polycomb Repressive Complex 2.PLoS genetics · 2016Article
- Establishment of three cell lines from Chinese giant salamander and their sensitivities to the wild-type and recombinant ranavirus.Veterinary research · 2015Article
- Cellular and molecular characterization of a novel primary osteoblast culture from the vertebrate model organism Xenopus tropicalis.Histochemistry and cell biology · 2015Article
- On the cellular and developmental lethality of a Xenopus nucleocytoplasmic hybrid.Communicative & integrative biology · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cell lines are useful tools to facilitate in vitro studies of many biological and molecular processes. We describe a new permanent fibroblast-type cell line obtained from disaggregated Xenopus tropicalis limb bud. The cell line population doubling time was ~24 h. Its karyotype was genetically stable with a chromosome number of 2n = 21 and a chromosome 10 trisomy. These cells could be readily transfected and expressed transgenes faithfully. We obtained stable transformants using transposon-based gene transfer technology. These cells responded to thyroid hormone and thus can provide a complementary research tool to study thyroid hormone signaling events. In conclusion, this cell line baptized "Speedy" should prove useful to couple in vitro and in vivo biological studies in the X. tropicalis frog model.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.