ArticleSurgical endoscopy2012
Endoscopic ultrasound-guided endoscopic necrosectomy of the pancreas: is irrigation necessary?
Article in Surgical endoscopy, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 39 citations in OpenAlex.
- Endoscopic management of complications of acute pancreatitis: an update on the field.Expert review of gastroenterology & hepatology · 2018Pooled it
- Endoscopic ultrasound-guided treatments: are we getting evidence based--a systematic review.World journal of gastroenterology · 2014Pooled it
- Guidelines for endoscopic treatment of postinflammatory pancreatic and peripancreatic fluid collections. Recommendations of the Endoscopic Surgery Section of the Association of Polish Surgeons, the Endoscopy Section of the Polish Society of Gastroenterology, the Polish Pancreatic Club, the Laparoscopic and Robotic Surgery Section of the Association of Polish Surgeons, and the Pancreatic Surgery Section of the Association of Polish Surgeons; formulated by an expert panel led by Prof. Mateusz Jagielski, MD, PhD.Wideochirurgia i inne techniki maloinwazyjne = Videosurgery and other miniinvasive techniques · 2025Review
- RWON Study: The Real-World Walled-off Necrosis Study.Clinical endoscopy · 2021Article
- Endotherapy for pancreatic necrosis: An update.JGH open : an open access journal of gastroenterology and hepatology · 2019Review
- Endoscopic necrosectomy of walled-off pancreatic necrosis using a lumen-apposing metal stent and irrigation technique.Surgical endoscopy · 2016Article
- Endoscopic necrosectomy under fluoroscopic guidance - a single center experience.Wideochirurgia i inne techniki maloinwazyjne = Videosurgery and other miniinvasive techniques · 2015Article
- Endoscopic ultrasound guided interventional procedures.World journal of gastrointestinal endoscopy · 2015Review
- Minimally invasive treatment of infected pancreatic necrosis.Przeglad gastroenterologiczny · 2014Review
- Transluminal retroperitoneal endoscopic necrosectomy with the use of hydrogen peroxide and without external irrigation: a novel approach for the treatment of walled-off pancreatic necrosis.Surgical endoscopy · 2013Article
- Is irrigation necessary during endoscopic necrosectomy of pancreatic necroses?Surgical endoscopy · 2012Article
- Controversies in EUS-guided treatment of walled-off necrosis.Endoscopic ultrasoundReview
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundFindings have shown endoscopic necrosectomy to be beneficial for patients with symptomatic pancreatic necrosis accessible for an endoscopic approach. The available studies show that endoscopic necrosectomy requires a multitude of subsequent procedures including repeat irrigation for removal of the necrotic material. This study aimed to investigate the need for additional irrigation in patients with necrotizing pancreatitis treated by endoscopic necrosectomy.
methodsThe study enrolled 35 consecutive patients (27 men) with a median age of 59 years who had pancreatic necrosis treated with endoscopic necrosectomy. Endoscopic ultrasound-guided internal drainage and consecutive endoscopic necrosectomy was combined with interval multistenting of the cavity. Neither endoscopic nor external irrigation was part of the procedure.
resultsAn average of 6.2 endoscopy sessions per patient were needed for access, necrosectomy, and stent management. The in-hospital mortality rate was 6% (2/35), including one procedure-related death resulting from postinterventional aspiration. The immediate morbidity rate was 9% (3/35). It was possible to achieve clinical remission for all the surviving patients with no additional surgery needed for management of the necroses. The median follow-up period was 23 months.
conclusionNeither endoscopic nor external flushing is needed for successful endoscopic treatment of symptomatic necroses. Even without irrigation, the outcome for patients treated with endoscopic necrosectomy is comparable to that described in the published data.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.