ArticleJournal of acquired immune deficiency syndromes (1999)2011
Control of medical comorbidities in individuals with HIV.
Article in Journal of acquired immune deficiency syndromes (1999), 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03198325 (Monitored Antiretroviral Pause in Chronic HIV-Infected Subjects With Long-Lasting Suppressed Viremia), which is not on this map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Monitored Antiretroviral Pause in Chronic HIV-Infected Subjects With Long-Lasting Suppressed Viremia (APACHE Study)
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.
- Barriers and facilitators to primary care engagement for people who inject drugs: A systematic review.Journal of nursing scholarship : an official publication of Sigma Theta Tau International Honor Society of Nursing · 2023Pooled it
- Trial
- Article
- Article
- Baltimore oral epidemiology, disease effects, and HIV evaluation study (BEEHIVE) study protocol: a prospective cohort study.BMC oral health · 2024Article
- Prevalence of hypertension and diabetes and associated risk factors among people living with human immunodeficiency virus in Southern Ethiopia.Frontiers in cardiovascular medicine · 2023Article
- Multimorbidity classes indicate differential patterns of health care engagement among people who inject drugs.Journal of substance abuse treatment · 2022Article
- Clinical Non-Adherence and Its Associated Factors Among HIV-Positive Pediatric Patients Attending HIV Care in South Gondar Zone Public Health Facilities, Northwest Ethiopia, 2021.HIV/AIDS (Auckland, N.Z.) · 2022Article
- Diabetes mellitus control in a large cohort of people with HIV in care-Washington, D.C.AIDS care · 2021Article
- Increased Retention in Care After a Palliative Care Referral Among People Living With HIV.Journal of acquired immune deficiency syndromes (1999) · 2020Article
- Food Insecurity and Unmet Needs Among Youth and Young Adults Living With HIV in the San Francisco Bay Area.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2019Article
- The association between a detectable HIV viral load and non-communicable diseases comorbidity in HIV positive adults on antiretroviral therapy in Western Cape, South Africa.BMC infectious diseases · 2019Article
- Blood Pressure, HIV, and Cocaine Use Among Ethnically and Racially Diverse Individuals.Southern medical journal · 2018Article
- Illness Perceptions, Medication Beliefs, and Adherence to Antiretrovirals and Medications for Comorbidities in Adults With HIV Infection and Hypertension or Chronic Kidney Disease.Journal of acquired immune deficiency syndromes (1999) · 2016Article
- A cross-sectional, population-based study measuring comorbidity among people living with HIV in Ontario.BMC public health · 2014Article
- Co-morbidities in persons infected with HIV: increased burden with older age and negative effects on health-related quality of life.AIDS patient care and STDs · 2013Article
- Multimorbidity With HIV: Views of Community-Based People Living With HIV and Other Chronic Conditions.The Journal of the Association of Nurses in AIDS Care : JANACArticle
- Protocol paper: Stepped wedge cluster randomized trial translating the ABCS into optimizing cardiovascular care for people living with HIV.Progress in cardiovascular diseasesArticle
- A pandemic of the poor: social disadvantage and the U.S. HIV epidemic.The American psychologistArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundWith improved combination antiretroviral therapy-related survival, diabetes and hypertension increasingly contribute to morbidity and mortality among individuals with HIV. However, there is limited data on diabetes and blood pressure control in this population. We examined whether virologic control is associated with control of diabetes and hypertension.
methodsWe examined HIV viral load, hemoglobin A1c (HbA1c), and blood pressure measurements from 70 diabetics and 291 hypertensives in the Johns Hopkins HIV Clinical Cohort, an urban, university-based cohort. All patients were treated for HIV and diabetes or hypertension. HbA1c and HIV-1 RNA were captured electronically from laboratory data, and blood pressure was collected electronically from vital signs taken at clinic visits. We used HIV-1 RNA values within 30 days of the HbA1c measurement or blood pressure measurement. The relationships between HIV-1 RNA and HbA1c and HIV-1 RNA and blood pressure were examined using separate random effects generalized least squares linear regression models.
resultsThe study sample was predominantly male and black, with a high prevalence of comorbid hepatitis C virus infection and psychiatric illness. In multivariable analysis, each log(10) increase in HIV-1 RNA was associated with higher HbA1c (β = 0.47 units, P < 0.001) among diabetics and higher mean arterial pressure among hypertensive patients (β = 1.95 mmHg, P < 0.001).
conclusionsSuboptimal control of HIV, indicated by detectable viral load, correlates with suboptimal control of diabetes and hypertension, indicated by higher HbA1c and mean arterial pressure. Achieving control of multiple medical comorbidities and HIV simultaneously may require expansion of current adherence interventions focused primarily on antiretroviral therapy.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.