ArticleSexually transmitted diseases2011
Effect of sexual activity on vaginal colonization with hydrogen peroxide-producing lactobacilli and Gardnerella vaginalis.
Article in Sexually transmitted diseases, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Sexually Transmitted Infections Treatment Guidelines, 2021.MMWR. Recommendations and reports : Morbidity and mortality weekly report. Recommendations and reports · 2021Guideline
- Sexually transmitted diseases treatment guidelines, 2015.MMWR. Recommendations and reports : Morbidity and mortality weekly report. Recommendations and reports · 2015Guideline
- Evaluating the Efficacy of Eradicating Gardnerella vaginalis Vaginal Colonization With Amoxicillin: A Randomized, Double-Blind, Phase 2 Study.Sexually transmitted diseases · 2022Trial
- Sexual practices have a significant impact on the vaginal microbiota of women who have sex with women.Scientific reports · 2019Trial
- Characteristics associated with Lactobacillus-depleted vaginal microbiota in women with different sexual behavior.Scientific reports · 2026Article
- Suggested Screening Criteria for Gardnerella vaginalis Based on Established Risk Factors.Cureus · 2024Review
- Clinical and Personal Lubricants Impact the Growth of Vaginal Lactobacillus Species and Colonization of Vaginal Epithelial Cells: An in Vitro Study.Sexually transmitted diseases · 2021Article
- The Impact of Semen Exposure on the Immune and Microbial Environments of the Female Genital Tract.Frontiers in reproductive health · 2020Article
- Incubation period and risk factors support sexual transmission of bacterial vaginosis in women who have sex with women.Sexually transmitted infections · 2019Article
- Characterization of the vaginal microbiome during cytolytic vaginosis using high-throughput sequencing.Journal of clinical laboratory analysis · 2019Article
- Comparisons of vaginal flora patterns among sexual behaviour groups of women: implications for the pathogenesis of bacterial vaginosis.Sexual health · 2018Article
- Women view key sexual behaviours as the trigger for the onset and recurrence of bacterial vaginosis.PloS one · 2017Article
- Article
- Characterization of the vaginal microbiota among sexual risk behavior groups of women with bacterial vaginosis.PloS one · 2013Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
backgroundBacterial vaginosis is associated with sexual activity, but mechanisms for this association are unclear. STUDY
designCross-sectional analysis of data from women reporting sex with women who provided information on sexual behaviors as part of a study of vaginal bacteria was conducted. Vaginal bacteria were detected by semiquantitative culture. Binomial regression with log-link evaluated associations between detection of bacteria and sexual behaviors reported to occur before enrollment. Linear regression evaluated associations between these behaviors and quantity of bacteria.
resultsOf the 320 women, 216 (68%) were colonized with H2O2-producing lactobacilli and 142 (44%) with Gardnerella vaginalis. Colonization with G. vaginalis was associated with >20 digital-vaginal sex acts (risk ratio, 2.01; 1.22, 3.29) or >10 toy-vaginal acts in the past 3 months (risk ratio, 1.76; 1.32, 2.36). Quantity of H2O2-producing lactobacilli was 1.3 log lower in colonized women reporting >10 acts of insertive vaginal sex-toy use in the past 3 months (95% confidence interval: -2.04, -0.56), 1.19 log lower with toy-vaginal sex in past 7 days (-1.75, -0.62), and 0.78 log lower in women sharing toys with a partner (-1.25, -0.31).
conclusionsVaginal insertive use and sharing of sex toys were associated with decreased quantities of H2O2-producing lactobacilli and higher risk of colonization with G. vaginalis.
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