Evidence map›Paper›PMID 22082290›Full record

ReviewFuture microbiology2011

Genetics of Coxiella burnetii: on the path of specialization.

Michael F Minnick, Rahul Raghavan

Abstract readReview
In one paragraph

Review in Future microbiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Review
  5. [Characteristics of Domestic Q Fever Cases, 2015-2021].Jugan geon-gang gwa jilbyeong · 2023
    Article
  6. A simple method for enrichment of phase I Coxiella burnetii.Journal of microbiological methods · 2023
    Article
  7. The intricate dance: host autophagy andFrontiers in microbiology · 2023
    Review
  8. Article
  9. The Intervening Sequence of Coxiella burnetii: Characterization and Evolution.Frontiers in cellular and infection microbiology · 2016
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Michael F MinnickDivision of Biological Sciences, The University of Montana, Missoula, MT 59812, USA. mike.minnick@mso.umt.edu
Rahul Raghavan
Yale University · US

Funding

Vascular stabilization as a broad theraprutic platform for biodefenseU54AI065357 · NIAID · COLORADO STATE UNIVERSITY-FORT COLLINS · PI BELISLE, JOHN T · 2005 to 2013
$77.5M
Role of Coxiella burnetii group I introns in growth modulationR21AI078125 · NIAID · UNIVERSITY OF MONTANA · PI MINNICK, MICHAEL F · 2009 to 2010
$389k
NIAID NIH HHS R21 AI078125NIAID NIH HHS U54 AI065357
6 · The paper itself

Abstract

Coxiella burnetii is an extremely infectious, zoonotic agent that causes Q fever in humans. With the exception of New Zealand, the bacterium is distributed worldwide. Coxiella is classified as a select agent based on its past and potential use as a bioweapon and its threat to public health. Despite decades of research, we know relatively little regarding Coxiella?s molecular pathogenesis, and a vaccine is not widely available. This article briefly reviews the unusual genetics of C. burnetii; a pathogen that retains telltale genetic mementos collected over the course of its evolutionary path from a free-living bacterium to an obligate intracellular parasite of eukaryotic host cell phagosomes. Understanding why these genetic elements are maintained may help us better understand the biology of this fascinating pathogen.

Indexed as

Evolution, MolecularCoxiella burnetiiDNA, BacterialGenes, BacterialModels, BiologicalPhagosomesVirulenceVirulence FactorsDNA, BacterialVirulence Factors

Identifiers

PMID22082290
PMCPMC4104754
OpenAlexW2169489743

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.