Evidence map›Paper›PMID 22081860›Full record

ArticleFree radical research2012

Fruit and vegetable and fried food consumption and 3-(2-deoxy-β-D-erythro-pentafuranosyl)pyrimido[1,2-α] purin-10(3H)-one deoxyguanosine adduct formation.

Marco Peluso, Armelle Munnia, Sara Piro, Adisorn Jedpiyawongse, Suleeporn Sangrajrang, Roger W Giese, Marcello Ceppi, Paolo Boffetta, Petcharin Srivatanakul

Abstract read
In one paragraph

Article in Free radical research, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
3.7field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Aberrant methylation of hypermethylated-in-cancer-1 and exocyclic DNA adducts in tobacco smokers.Toxicological sciences : an official journal of the Society of Toxicology · 2014
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 4 countries.

Marco PelusoCancer Risk Factor Branch, ISPO-Cancer Prevention and Research Institute, Florence, Italy. m.peluso@ispo.toscana.it
Armelle Munnia
Sara Piro
Adisorn Jedpiyawongse
Suleeporn Sangrajrang
Roger W Giese
Marcello Ceppi
Paolo Boffetta
Petcharin Srivatanakul
National Cancer Institute of Thailand · THPiedmont Reference Center for Epidemiology and Cancer Prevention · ITInternational Prevention Research Institute · FRNortheastern University · US

Funding

Research Experiences and Training Coordination CoreP42ES017198 · NIEHS · NORTHEASTERN UNIVERSITY · PI ALSHAWABKEH, AKRAM N · 2010 to 2024
$38.6M
NIEHS NIH HHS P42 ES017198NIEHS NIH HHS P42ES017198
6 · The paper itself

Abstract

Diet has been shown to modulate M(1)dG adduct, a biomarker of oxidative stress and lipid peroxidation. Thus, we analysed the association between diet and M(1)dG in 120 controls and 67 Map Ta Phut industrial estate workers in Rayong, Thailand, to evaluate the influence of fruit and vegetables, and fried and charcoal-grilled/barbecued food consumption on M(1)dG. M(1)dG was decreased in controls reporting to consume 14-17 servings/week of fruit and vegetables (mean ratio [MR]= 0.35, CI 0.18-0.69, p< 0.05). Conversely, a non-statistically significant M(1)dG increment was detected in controls consuming 9-18 servings/week of fried food (MR = 1.33, CI 0.88-2.00, p = 0.168). No effect of charcoal-grilled/barbecued food was found. No effect of diet was observed in workers. An association with smoking was observed in controls (MR = 1.88, CI 1.14-3.10, p < 0.05), but not in workers. M(1)dG can induce mutations and/or methylation changes within the promoter regions of cancer-related genes, thus promotion of healthy eating practices should be recommended.

Indexed as

DietFruitVegetablesAdultDeoxyguanosineDNADNA AdductsFeeding BehaviorFemaleHumansLipid PeroxidationMaleMalondialdehydeMass SpectrometryOxidative StressPurine Nucleosides3-(2'-deoxy-beta-D-erythro-pentofuranosyl)pyrimido(1,2-alpha)purin-10(3H)-onecalf thymus DNADeoxyguanosineDNADNA AdductsMalondialdehydePurine Nucleosides

Identifiers

PMID22081860
PMCPMC3293701
OpenAlexW2160925064

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.