ArticleJournal of neurology2012
Striatal hypermetabolism in limbic encephalitis.
Article in Journal of neurology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 44 citations in OpenAlex.
- Imaging biomarkers in antibody-mediated autoimmune encephalitis.Quantitative imaging in medicine and surgery · 2025Article
- Quantitative brainAnnals of clinical and translational neurology · 2024Article
- Dopamine, Immunity, and Disease.Pharmacological reviews · 2023Review
- Decrease in the cortex/striatum metabolic ratio on [European journal of nuclear medicine and molecular imaging · 2022Article
- Periodic electroencephalographic discharges and epileptic spasms involve cortico-striatal-thalamic loops on Arterial Spin Labeling Magnetic Resonance Imaging.Brain communications · 2022Article
- Parainfectious encephalitis in COVID-19: "The Claustrum Sign".Journal of neurology · 2021Article
- Article
- Diagnosis and Management of Autoimmune Dementia.Current treatment options in neurology · 2019Review
- Metabolic topography of autoimmune non-paraneoplastic encephalitis.Neuroradiology · 2018Article
- Semi-quantitative analysis of cerebral FDG-PET reveals striatal hypermetabolism and normal cortical metabolism in a case of VGKCC limbic encephalitis.The neuroradiology journal · 2017Article
- Reversible Bilateral Striatal Hypermetabolism in a Patient with Leucine-Rich Glioma Inactivated-1 Encephalitis.Journal of clinical neurology (Seoul, Korea) · 2016Article
- Movement disorders in systemic lupus erythematosus and the antiphospholipid syndrome.Journal of neural transmission (Vienna, Austria : 1996) · 2013Review
- Cerebral FDG-PET and MRI findings in autoimmune limbic encephalitis: correlation with autoantibody types.Journal of neurology · 2013Article
- Chorea, a little-known manifestation in systemic lupus erythematosus: short literature review and four case reports.Pediatric rheumatology online journal · 2013Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Striatal hypermetabolism on 18FDG-PET scan is a neuroradiological finding that has been described in association with autoimmune disorders such as Sydenham chorea, lupus or antiphospholipid syndrome. Here, we report three patients with non-paraneoplastic limbic encephalitis characterized by 18FDG-PET hypermetabolism of both striata, in contrast with diffuse hypometabolism in the rest of the brain. All patients developed subacute dementia, and antibodies to voltage-gated potassium channels were found in all cases. Brain metabolism and neurological status improved within a few months of immunosuppressive therapy. The finding of striatal hypermetabolism on 18FDG-PET images could thus be highly indicative of limbic encephalitis associated with anti-neuropil antibodies. It could be of significant help in the diagnosis of this rare and treatable condition, and may also provide a useful marker of disease outcome.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.