ArticleNature2011
Neuronal filtering of multiplexed odour representations.
Article in Nature, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers.
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Who cites it
56 citing papers in PubMed, 112 citations in OpenAlex.
- Representational learning by optimization of neural manifolds in an olfactory memory network.Nature neuroscience · 2026Article
- Simultaneous encoding of sensory features: the role of multiplexing and noise in tactile perception and neural representation.Biological reviews of the Cambridge Philosophical Society · 2026Review
- Geometry and dynamics of representations in a precisely balanced memory network related to olfactory cortex.eLife · 2025Article
- Common principles for odour coding across vertebrates and invertebrates.Nature reviews. Neuroscience · 2024Review
- Spatially resolved cell atlas of the teleost telencephalon and deep homology of the vertebrate forebrain.Communications biology · 2024Article
- Pheromone Perception in Fish: Mechanisms and Modulation by Internal Status.Integrative and comparative biology · 2023Review
- Spatially resolved cell atlas of the teleost telencephalon and deep homology of the vertebrate forebrain.bioRxiv : the preprint server for biology · 2023Article
- All-optical manipulation of the Drosophila olfactory system.Scientific reports · 2022Article
- High-performance microbial opsins for spatially and temporally precise perturbations of large neuronal networks.Neuron · 2022Article
- A database and deep learning toolbox for noise-optimized, generalized spike inference from calcium imaging.Nature neuroscience · 2021Article
- A two-compartment model of synaptic computation and plasticity.Molecular brain · 2020Review
- Associative conditioning remaps odor representations and modifies inhibition in a higher olfactory brain area.Nature neuroscience · 2019Article
- Differentially synchronized spiking enables multiplexed neural coding.Proceedings of the National Academy of Sciences of the United States of America · 2019Article
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- Detection of Activation Sequences in Spiking-Bursting Neurons by means of the Recognition of Intraburst Neural Signatures.Scientific reports · 2018Article
- Rapid olfactory discrimination learning in adult zebrafish.Experimental brain research · 2018Article
- Optogenetic stimulation of complex spatio-temporal activity patterns by acousto-optic light steering probes cerebellar granular layer integrative properties.Scientific reports · 2018Article
- Methods for Mapping Neuronal Activity to Synaptic Connectivity: Lessons From Larval Zebrafish.Frontiers in neural circuits · 2018Article
- A Rate-Reduced Neuron Model for Complex Spiking Behavior.Journal of mathematical neuroscience · 2017Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Neuronal activity patterns contain information in their temporal structure, indicating that information transfer between neurons may be optimized by temporal filtering. In the zebrafish olfactory bulb, subsets of output neurons (mitral cells) engage in synchronized oscillations during odour responses, but information about odour identity is contained mostly in non-oscillatory firing rate patterns. Using optogenetic manipulations and odour stimulation, we found that firing rate responses of neurons in the posterior zone of the dorsal telencephalon (Dp), a target area homologous to olfactory cortex, were largely insensitive to oscillatory synchrony of mitral cells because passive membrane properties and synaptic currents act as low-pass filters. Nevertheless, synchrony influenced spike timing. Moreover, Dp neurons responded primarily during the decorrelated steady state of mitral cell activity patterns. Temporal filtering therefore tunes Dp neurons to components of mitral cell activity patterns that are particularly informative about precise odour identity. These results demonstrate how temporal filtering can extract specific information from multiplexed neuronal codes.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.