Evidence map›Paper›PMID 22080607›Full record

ReviewProceedings of the National Academy of Sciences of the United States of America2011

Dendritic SNAREs add a new twist to the old neuron theory.

Saak V Ovsepian, J Oliver Dolly

Abstract readReview
In one paragraph

Review in Proceedings of the National Academy of Sciences of the United States of America, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. Article
  2. Exosomes in the Diagnosis and Treatment of Renal Cell Cancer.International journal of molecular sciences · 2023
    Review
  3. Article
  4. Molecular Biomarkers of Neuronal Injury in Epilepsy Shared with Neurodegenerative Diseases.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2023
    Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Dendritic Localization and Exocytosis of NAAG in the Rat Hippocampus.Cerebral cortex (New York, N.Y. : 1991) · 2020
    Article
  10. Review
  11. Amyloid Plaques of Alzheimer's Disease as Hotspots of Glutamatergic Activity.The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry · 2019
    Review
  12. Article
  13. Article
  14. Review
  15. Dendritic Release of Neurotransmitters.Comprehensive Physiology · 2016
    Review
  16. Article
  17. Article
  18. Somatodendritic dopamine release: recent mechanistic insights.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2015
    Review
  19. Multiple signalling modalities mediated by dendritic exocytosis of oxytocin and vasopressin.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2015
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Saak V OvsepianInternational Centre for Neurotherapeutics, Dublin City University, Glasnevin, Dublin 9, Ireland.
J Oliver Dolly

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dendritic exocytosis underpins a broad range of integrative and homeostatic synaptic functions. Emerging data highlight the essential role of SNAREs in trafficking and fusion of secretory organelles with release of peptides and neurotransmitters from dendrites. This Perspective analyzes recent evidence inferring axo-dendritic polarization of vesicular release machinery and pinpoints progress made with existing challenges in this rapidly progressing field of dendritic research. Interpreting the relation of new molecular data to physiological results on secretion from dendrites would greatly advance our understanding of this facet of neuronal mechanisms.

Indexed as

CalciumCell PolarityDendritesMembrane FusionModels, BiologicalNeuronsSNARE ProteinsSynapsesTransport VesiclesCalciumSNARE Proteins

Identifiers

PMID22080607
PMCPMC3228427

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.