Evidence map›Paper›PMID 22080473›Full record

ArticleEuropace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology2012

Efficacy and safety of ventricular tachycardia ablation with mechanical circulatory support compared with substrate-based ablation techniques.

T Jared Bunch, Andy Darby, Heidi T May, Michael Ragosta, D Scott Lim, Angela M Taylor, John P DiMarco, Gorav Ailawadi, James R Revenaugh, J Peter Weiss and 1 more

Open access · bronzeAbstract readComparative Study
In one paragraph

Article in Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 4 pooled it
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 4 syntheses or guidelines pooled it, 64 citations in OpenAlex.

  1. Preemptive mechanical circulatory support in ventricular tachycardia ablation: A systematic review and meta-analysis.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2026
    Pooled it
  2. Pooled it
  3. Complication rates following ventricular tachycardia ablation in ischaemic and non-ischaemic cardiomyopathies: a systematic review.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2022
    Pooled it
  4. Percutaneous ventricular assist device in ventricular tachycardia ablation: a systematic review and meta-analysis.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2019
    Pooled it
  5. Article
  6. Percutaneous mechanical support in catheter ablation of ventricular arrhythmias: hype or hope?Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2024
    Review
  7. Complications of catheter ablation for ventricular tachycardia.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2023
    Review
  8. Article
  9. Review
  10. Article
  11. Mechanical circulatory support in ventricular arrhythmias.Frontiers in cardiovascular medicine · 2022
    Review
  12. Article
  13. Article
  14. Review
  15. Percutaneous left ventricular assist deviceChronic diseases and translational medicine · 2018
    Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

T Jared BunchIntermountain Medical Center, Salt Lake City, UT, USA.
Andy Darby
Heidi T May
Michael Ragosta
D Scott Lim
Angela M Taylor
John P DiMarco
Gorav Ailawadi
James R Revenaugh
J Peter Weiss
Srijoy Mahapatra
University of Virginia Health System · USIntermountain Medical Center · USUniversity of Utah · US

Funding

Early Noninvasive Detection of Myocardial Microbascular Dysfunction in DiabetesK23HL093118 · NHLBI · UNIVERSITY OF VIRGINIA · PI TAYLOR, ANGELA M · 2009 to 2013
$634k
NHLBI NIH HHS K23 HL093118
6 · The paper itself

Abstract

aimsCatheter ablation of ventricular tachycardia (VT) can be limited by haemodynamic instability. In these cases, substrate-based ablation is typically performed. An alternative is to perform activation and entrainment mapping during VT supported by a percutaneous left ventricular assist device (pVAD). We sought to compare the complication and success rates of pVAD-assisted VT ablation with scar-based techniques. METHODS AND

resultsThirteen consecutive patients with haemodynamically unstable VT underwent pVAD-assisted ablation (pVAD group) and were retrospectively compared with 18-matched patients undergoing a substrate-based VT ablation (non-pVAD group). There was no significant difference in age or ejection fraction between the groups although pVAD patients tended to have more shocks in the preceding months. Procedure times were longer for the pVAD group. The number of monomorphic VTs induced was greater in the pVAD group (3.2 vs. 1.6, P= 0.04); however, after ablation, there was no difference in inducibility between the pVAD and non-pVAD group (10 of 13 vs. 12 of 18; 77 vs. 67%, P = 0.69). There was no difference in acute complications including stroke or death. At 9 ± 3 months, 1-year freedom from implantable cardioverter-defibrillator (ICD) shocks/therapies for sustained VT were similar (P= 0.96). In multivariable analysis, the absence of atrial fibrillation (hazard ratio=0.15, P= 0.04) was associated with a lower incidence of ICD shocks.

conclusionsIn high-risk patients, pVAD-assisted VT ablation guided by activation and entrainment mapping is a feasible alternative to substrate mapping and allows outcomes comparable to substrate mapping.

Indexed as

Heart-Assist DevicesAtrial FibrillationCatheter AblationCicatrixDisease-Free SurvivalElectrophysiologic Techniques, CardiacFemaleFollow-Up StudiesHumansIncidenceKaplan-Meier EstimateMaleMiddle AgedPostoperative ComplicationsRetrospective StudiesRisk Factors

Identifiers

PMID22080473
PMCPMC3598428
OpenAlexW2083443337

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.