Evidence map›Paper›PMID 22080300›Full record

ArticleImmunogenetics2012

Immunogenetic Management Software: a new tool for visualization and analysis of complex immunogenetic datasets.

Z P Johnson, R D Eady, S F Ahmad, S Agravat, T Morris, J Else, S M Lank, R W Wiseman, D H O'Connor, M C T Penedo and 2 more

Open access · greenAbstract read
In one paragraph

Article in Immunogenetics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Evidence for kidney rejection after combined bone marrow and renal transplantation despite ongoing whole-blood chimerism in rhesus macaques.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2012
    Article
  9. Nonhuman primate transplant models finally evolve: detailed immunogenetic analysis creates new models and strengthens the old.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2012
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Z P JohnsonYerkes National Primate Research Center, Emory University, Atlanta, GA 30322, USA.
R D Eady
S F Ahmad
S Agravat
T Morris
J Else
S M Lank
R W Wiseman
D H O'Connor
M C T Penedo
C P Larsen
L S Kean
Emory University · USUniversity of Wisconsin–Madison · USUniversity of California, Davis · US

Funding

YNPRC NHP CLINICAL MEDICINE RESIDENCY PROGRAM - SUPPLEMENTP51RR000165 · NCRR · EMORY UNIVERSITY · PI ALTMAN, JOHN DAVID · 1985 to 2011
$114.0M
Transplant Tolerance in Non-Human PrimatesU19AI051731 · NIAID · UNIVERSITY OF WESTERN ONTARIO · PI LARSEN, CHRISTIAN P. · 2002 to 2022
$54.1M
GENETICALLY DEFINED HERPES/RETROVIRUS SPF MACAQUES: AIDS: VACCINE DVMTU24RR018144 · NCRR · UNIVERSITY OF CALIFORNIA DAVIS · PI LERCHE, NICHOLAS WILLIAM · 2002 to 2011
$15.7M
SPF BREEDING COLONIES AT THE YERKES NPRC: AIDS, THERAPEUTIC AGENT DVMTU24RR018109 · NCRR · EMORY UNIVERSITY · PI ELSE, JAMES GIBSON · 2002 to 2011
$13.8M
Novel Biologic Therapies for GVHDR01HL095791 · NHLBI · SEATTLE CHILDREN'S HOSPITAL · PI KEAN, LESLIE S · 2010 to 2025
$13.3M
PRODUCTION OF PEDIGREED SPF RHESUS MACAQUES: HIV VACCINE DVMTU42RR016023 · NCRR · UNIVERSITY OF CALIFORNIA DAVIS · PI HYDE, DALLAS MELVIN · 2000 to 2011
$13.0M
TRANSPLANT TOLERANCE--COSTIMULATION, CYTOKINES &CHIMERISMP01AI044644 · NIAID · EMORY UNIVERSITY · PI LARSEN, CHRISTIAN P. · 1998 to 2010
$9.7M
SPF Breeding Colonies at the Yerkes NPRCU24OD011023 · OD · EMORY UNIVERSITY · PI COHEN, JOYCE KIMBERLY · 2012 to 2017
$8.2M
Innate Immunity and Transplantation ToleranceK08AI065822 · NIAID · EMORY UNIVERSITY · PI KEAN, LESLIE S · 2006 to 2009
$476k
NCRR NIH HHS 2U24 RR018109NCRR NIH HHS P51 RR000165NCRR NIH HHS RR00165NCRR NIH HHS U24 RR018109NCRR NIH HHS U24 RR018144NCRR NIH HHS U24 RR18144NCRR NIH HHS U42 RR016023NCRR NIH HHS U42-RR16023NHLBI NIH HHS 1R01 HL095791NHLBI NIH HHS R01 HL095791NIAID NIH HHS 2P01 AI044644NIAID NIH HHS 2U19 AI051731NIAID NIH HHS 5K08 AI065822NIAID NIH HHS K08 AI065822NIAID NIH HHS P01 AI044644NIAID NIH HHS U19 AI051731NIH HHS U24 OD011023PHS HHS HHSN266200400088C/N01-A1-40088
6 · The paper itself

Abstract

Here we describe the Immunogenetic Management Software (IMS) system, a novel web-based application that permits multiplexed analysis of complex immunogenetic traits that are necessary for the accurate planning and execution of experiments involving large animal models, including nonhuman primates. IMS is capable of housing complex pedigree relationships, microsatellite-based MHC typing data, as well as MHC pyrosequencing expression analysis of class I alleles. It includes a novel, automated MHC haplotype naming algorithm and has accomplished an innovative visualization protocol that allows users to view multiple familial and MHC haplotype relationships through a single, interactive graphical interface. Detailed DNA and RNA-based data can also be queried and analyzed in a highly accessible fashion, and flexible search capabilities allow experimental choices to be made based on multiple, individualized and expandable immunogenetic factors. This web application is implemented in Java, MySQL, Tomcat, and Apache, with supported browsers including Internet Explorer and Firefox on Windows and Safari on Mac OS. The software is freely available for distribution to noncommercial users by contacting Leslie.kean@emory.edu. A demonstration site for the software is available at http://typing.emory.edu/typing_demo , user name: imsdemo7@gmail.com and password: imsdemo.

Indexed as

SoftwareAlgorithmsAllelesAnimalsComputational BiologyGenotypeHaplotypesHistocompatibility Antigens Class IHumansImmunogeneticsInternetMajor Histocompatibility ComplexMicrosatellite RepeatsPedigreeReproducibility of ResultsSequence Analysis, DNAHistocompatibility Antigens Class I

Identifiers

PMID22080300
PMCPMC3514553
OpenAlexW2039090615

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.