Evidence map›Paper›PMID 22080266›Full record

ArticleClinical infectious diseases : an official publication of the Infectious Diseases Society of America2011

Mycoplasma genitalium: should we treat and how?

Lisa E Manhart, Jennifer M Broad, Matthew R Golden

Open access · bronzeAbstract read
In one paragraph

Article in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed, 1 pooled it
9.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 1 synthesis or guideline pooled it, 145 citations in OpenAlex.

  1. Sexually transmitted diseases treatment guidelines, 2015.MMWR. Recommendations and reports : Morbidity and mortality weekly report. Recommendations and reports · 2015
    Guideline
  2. Mycoplasma genitalium Infection in Kenyan and US Women.Sexually transmitted diseases · 2018
    Trial
  3. Trial
  4. Comparative Epidemiology and Co-Detection ofPathogens (Basel, Switzerland) · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. To Screen or Not to Screen-Controversies in Testing forJournal of the Association of Medical Microbiology and Infectious Disease Canada = Journal officiel de l'Association pour la microbiologie medicale et l'infectiologie Canada · 2024
    Article
  11. Article
  12. Article
  13. Article
  14. Prevalence ofHealthcare (Basel, Switzerland) · 2023
    Article
  15. Review
  16. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Lisa E ManhartDepartments of Epidemiology, University of Washington, Center for AIDS and STD, 325 9th Ave, Box 359931, Seattle, WA 98104, USA. lmanhart@u.washington.edu
Jennifer M Broad
Matthew R Golden
Public Health – Seattle & King County · USUniversity of Washington · US

Funding

University of Washington STI-TM Cooperative Research CtrU19AI031448 · NIAID · UNIVERSITY OF WASHINGTON · PI HOLMES, KING K. · 1995 to 2010
$15.2M
Ureaplasmas in acute and persistent urethritis: clinical implicationsR01AI072728 · NIAID · UNIVERSITY OF WASHINGTON · PI MANHART, LISA E · 2007 to 2010
$1.4M
NIAID NIH HHS R01 AI072728NIAID NIH HHS U19 AI031448NIAID NIH HHS U19 AI31448
6 · The paper itself

Abstract

Mycoplasma genitalium is associated with acute and chronic urethritis in men. Existing data on infection in women are limited and inconsistent but suggest that M. genitalium is associated with urethritis, cervicitis, pelvic inflammatory disease, and possibly female infertility. Data are inconclusive regarding the role of M. genitalium in adverse pregnancy outcomes and ectopic pregnancy. Available data suggest that azithromycin is superior to doxycycline in treating M. genitalium infection. However, azithromycin-resistant infections have been reported in 3 continents, and the proportion of azithromycin-resistant M. genitalium infection is unknown. Moxifloxacin is the only drug that currently seems to uniformly eradicate M. genitalium. Detection of M. genitalium is hampered by the absence of a commercially available diagnostic test. Persons with persistent pelvic inflammatory disease or clinically significant persistent urethritis or cervicitis should be tested for M. genitalium, if possible. Infected persons who have not previously received azithromycin should receive that drug. Persons in whom azithromycin therapy fails should be treated with moxifloxicin.

Indexed as

Anti-Bacterial AgentsAza CompoundsAzithromycinDoxycyclineDrug Resistance, BacterialFemaleFluoroquinolonesHumansInfertility, FemaleMaleMoxifloxacinMycoplasma genitaliumMycoplasma InfectionsPelvic Inflammatory DiseasePregnancyPregnancy, EctopicAnti-Bacterial AgentsAza CompoundsAzithromycinDoxycyclineFluoroquinolonesMoxifloxacinQuinolines

Identifiers

PMID22080266
PMCPMC3213402
OpenAlexW2162246504

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.