Evidence map›Paper›PMID 22078548›Full record

ArticleEnfermedades infecciosas y microbiologia clinica2012

Phenotypic and molecular characterization of serogroup C Neisseria meningitidis associated with an outbreak in Bahia, Brazil.

Maria Cecília O Gorla, Ana Paula S de Lemos, Márcia Quaresma, Rita Vilasboas, Orgali Marques, Márcia U de Sá, Cinthya T Ogassavara, Maria Cristina de C Brandileone, Lee H Harrison, Juarez Dias

Abstract read
In one paragraph

Article in Enfermedades infecciosas y microbiologia clinica, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Phenotypic characterization ofAccess microbiology · 2020
    Article
  5. Article
  6. Article
  7. Seroprevalence of bactericidal antibodies against serogroup B and C Meningococci in a University Hospital.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2017
    Article
  8. Observational
  9. Article
  10. Article
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  12. Short-term and long-term antibody response by mice after immunization against Neisseria meningitidis B or diphtheria toxoid.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2013
    Article
  13. Article
  14. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Maria Cecília O GorlaDivision of Medical Biology, Bacteriology Department, Adolfo Lutz Institute, Brazil. mcgorla@ial.sp.gov.br
Ana Paula S de Lemos
Márcia Quaresma
Rita Vilasboas
Orgali Marques
Márcia U de Sá
Cinthya T Ogassavara
Maria Cristina de C Brandileone
Lee H Harrison
Juarez Dias

Funding

Real-Time PCR for Diagnosis of Culture-Negative Bacterial Meningitis in S?o PauloD43TW006592 · FIC · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI HARRISON, LEE H · 2004 to 2013
$1.7M
Shedding of HIV In Semen Despite Antiretroviral TherapyK24AI052788 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI HARRISON, LEE H · 2002 to 2012
$1.4M
FIC NIH HHS D43 TW006592FIC NIH HHS D43TW006592NIAID NIH HHS K24 AI052788NIAID NIH HHS K24 AI52788
6 · The paper itself

Abstract

objectiveTo characterize meningococcal strains isolated from five cases of meningococcal disease (MD) associated with an outbreak in Trancoso - BA, occurred in October 2009. All cases, with the exception of a 39-year-old male, attended a dance party with approximately 1000 youngsters in a rural site. MATERIALS AND

methodsThe epidemiological investigation was conducted by the Epidemiological Surveillance Service of Bahia State. Meningococcal strains were characterized at Adolfo Lutz Institute, the Brazilian National Reference Laboratory for Bacterial Meningitis by conventional techniques (serotype, serosubtype and antimicrobial susceptibility test) and by molecular methods (Pulsed-field gel electrophoresis - PFGE and Multilocus Sequence Typing - MLST).

resultsThe PFGE showed 2 closely related restriction profiles, designated as PFGE types A and A1, having 92% relatedness to each other. MLST characterization showed both A and A1 clones were ST-3780, which belongs to the ST-103 complex. All isolates displayed the phenotype C:23:P1.5 and were susceptible to all antibiotics tested.

conclusionsThis is the first reported MD outbreak associated with serogroup C ST-103 complex in Brazil, as well as the party and illicit drug-use associated outbreak.

Indexed as

Disease OutbreaksAdolescentAdultBrazilContact TracingCrowdingDNA, BacterialDrug Resistance, Multiple, BacterialElectrophoresis, Gel, Pulsed-FieldFemaleGenome, BacterialHumansMaleMeningitis, MeningococcalNeisseria meningitidis, Serogroup CPhenotypeDNA, Bacterial

Identifiers

PMID22078548
PMCPMC4807656

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.