Evidence map›Paper›PMID 22078280›Full record

ArticleEnvironmental health : a global access science source2011

Influence of mercury exposure on blood pressure, resting heart rate and heart rate variability in French Polynesians: a cross-sectional study.

Beatriz Valera, Eric Dewailly, Paul Poirier, Emilie Counil, Edouard Suhas

Open access · goldAbstract read
In one paragraph

Article in Environmental health : a global access science source, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 4 pooled it
2.1field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 4 syntheses or guidelines pooled it, 40 citations in OpenAlex.

  1. Pooled it
  2. Chronic mercury exposure and blood pressure in children and adolescents: a systematic review.Environmental science and pollution research international · 2019
    Pooled it
  3. Pooled it
  4. Mercury Exposure and Heart Rate Variability: a Systematic Review.Current environmental health reports · 2015
    Pooled it
  5. Article
  6. Contaminant Metals and Cardiovascular Health.Journal of cardiovascular development and disease · 2023
    Review
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  13. Heart Rate Variability, Heart Rate Recovery, and Heart Rate Turbulence Represent Different Components of the Cardiac Autonomic Nervous System.Medical principles and practice : international journal of the Kuwait University, Health Science Centre · 2017
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Beatriz ValeraAxe Santé des Populations et Environnement, Centre de Recherche du CHUQ, 2875 Boulevard Laurier, Québec G1V 2M2, Canada.
Eric Dewailly
Paul Poirier
Emilie Counil
Edouard Suhas
Université Laval · CAÉcole des Hautes Études en Santé Publique · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPopulations which diet is rich in seafood are highly exposed to contaminants such as mercury, which could affect cardiovascular risk factors

objectiveTo assess the associations between mercury and blood pressure (BP), resting heart rate (HR) and HR variability (HRV) among French Polynesians

methodsData were collected among 180 adults (≥ 18 years) and 101 teenagers (12-17 years). HRV was measured using a two-hour ambulatory electrocardiogram (Holter) and BP was measured using a standardized protocol. The association between mercury and HRV and BP parameters was studied using analysis of variance (ANOVA) and analysis of covariance (ANCOVA)

resultsAmong teenagers, the high frequency (HF) decreased between the 2nd and 3rd tertile (380 vs. 204 ms2, p = 0.03) and a similar pattern was observed for the square root of the mean squared differences of successive R-R intervals (rMSSD) (43 vs. 30 ms, p = 0.005) after adjusting for confounders. In addition, the ratio low/high frequency (LF/HF) increased between the 2nd and 3rd tertile (2.3 vs. 3.0, p = 0.04). Among adults, the standard deviation of R-R intervals (SDNN) tended to decrease between the 1st and 2nd tertile (84 vs. 75 ms, p = 0.069) after adjusting for confounders. Furthermore, diastolic BP tended to increase between the 2nd and 3rd tertile (86 vs. 91 mm Hg, p = 0.09). No significant difference was observed in resting HR or pulse pressure (PP)

conclusionsMercury was associated with decreased HRV among French Polynesian teenagers while no significant association was observed with resting HR, BP, or PP among teenagers or adults.

Indexed as

Blood PressureEnvironmental ExposureHeart RateAdolescentAdultAgedAnalysis of VarianceChromatography, High Pressure LiquidCross-Sectional StudiesElectrocardiographyEnvironmental PollutantsFatty Acids, UnsaturatedFemaleHumansMaleMass SpectrometryEnvironmental PollutantsFatty Acids, UnsaturatedMercurySelenium

Identifiers

PMID22078280
PMCPMC3228671
OpenAlexW2132655568

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.