ArticleClinical journal of the American Society of Nephrology : CJASN2012
Racial differences in the incidence of chronic kidney disease.
Article in Clinical journal of the American Society of Nephrology : CJASN, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
45 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Apolipoprotein L1 gene variants and kidney disease in patients with HIV: a systematic review and meta-analysis.Journal of nephrology · 2023Pooled it
- Association of sickle cell trait with chronic kidney disease and albuminuria in African Americans.JAMA · 2014Pooled it
- KNOW-CKD (KoreaN cohort study for Outcome in patients With Chronic Kidney Disease): design and methods.BMC nephrology · 2014Trial
- Proteomic risk score for early prediction of kidney disease progression in individuals with APOL1 high-risk genotypes.Nature medicine · 2026Article
- A Comprehensive Report on the Self-Reported Chronic Kidney Disease Patients in the NHANES Cross-Sectional Cohort from 2001 to 2020.Kidney & blood pressure research · 2026Article
- Machine learning-based prediction models in medical decision-making in kidney disease: patient, caregiver, and clinician perspectives on trust and appropriate use.Journal of the American Medical Informatics Association : JAMIA · 2025Article
- Differing sensitivities to angiotensin converting enzyme inhibition of kidney disease mediated by APOL1 high-risk variants G1 and G2.Kidney international · 2024Article
- Cardiovascular Disease in Chronic Kidney Disease: Implications of Cardiorespiratory Fitness, Race, and Sex.Reviews in cardiovascular medicine · 2024Review
- Examining chronic kidney disease screening frequency among diabetics: a POMDP approach.Health care management science · 2024Article
- Association between the Oxidative Balance Score and Incident Chronic Kidney Disease in Adults.Antioxidants (Basel, Switzerland) · 2023Article
- Racial Differences and Contributory Cardiovascular and Non-Cardiovascular Risk Factors Towards Chronic Kidney Disease Progression.Vascular health and risk management · 2023Article
- The KoreaN Cohort Study for Outcomes in Patients With Chronic Kidney Disease (KNOW-CKD): A Korean Chronic Kidney Disease Cohort.Journal of preventive medicine and public health = Yebang Uihakhoe chi · 2022Article
- Knowledge and Risk Perceptions of Chronic Kidney Disease Risk Factors among Women of Childbearing Age in Lagos State, Nigeria: From a Health Demography Approach.International journal of nephrology · 2022Article
- Association of Educational Attainment With Incidence of CKD in Young Adults.Kidney international reports · 2020Article
- Decline in kidney function over the course of adulthood and cognitive function in midlife.Neurology · 2020Article
- The KNOW-CKD Study: What we have learned about chronic kidney diseases.Kidney research and clinical practice · 2020Review
- Article
- Points to consider in cardiovascular disease risk management among patients with rheumatoid arthritis living in South Africa, an unequal middle income country.BMC rheumatology · 2020Article
- N-Terminal Pro-B-Type Natriuretic Peptide Is a Predictor of Chronic Kidney Disease in an Asian General Population - The Ohasama Study.Circulation reports · 2019Article
- Impact of chronic kidney disease on mortality: A nationwide cohort study.Kidney research and clinical practice · 2019Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
BACKGROUND AND
objectivesThe incidence of ESRD is higher in African Americans than in whites, despite reports of a similar or lower prevalence of CKD. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: This study compared the incidence of CKD among young African-American and white adults over 20 years of follow-up in the community-based Coronary Artery Risk Development in Young Adults study. Participants included 4119 adults, 18-30 years of age, with an estimated GFR (eGFR) ≥60 ml/min per 1.73 m(2) at baseline. Incident CKD was defined as an eGFR <60 ml/min per 1.73 m(2) and a ≥25% decline in eGFR at study visits conducted 10, 15, and 20 years after baseline.
resultsAt baseline, the mean age of African Americans and whites was 24 and 26 years, respectively (P<0.001), and 56% and 53% of participants, respectively, were women (P=0.06). There were 43 incident cases of CKD during follow-up, 29 (1.4%) among African Americans and 14 (0.7%) among whites (P=0.02). The age- and sex-adjusted hazard ratio (HR) for incident CKD comparing African Americans to whites was 2.56 (95% confidence interval [95% CI], 1.35-5.05). After further adjustment for body mass index, systolic BP, fasting plasma glucose, and HDL cholesterol, the HR was 2.51 (95% CI, 1.25-5.05). After multivariable adjustment including albuminuria at year 10, the HR for CKD at year 15 or 20 was 1.12 (95% CI, 0.52-2.41).
conclusionsIn this study, the 20-year CKD incidence was higher among African Americans than whites, a difference that is explained in part by albuminuria.
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