Evidence map›Paper›PMID 22076697›Full record

ArticleAnnals of behavioral medicine : a publication of the Society of Behavioral Medicine2012

Benefits of adherence to psychotropic medications on depressive symptoms and antiretroviral medication adherence among men and women living with HIV/AIDS.

Dean G Cruess, Seth C Kalichman, Christine Amaral, Connie Swetzes, Chauncey Cherry, Moira O Kalichman

Abstract read
In one paragraph

Article in Annals of behavioral medicine : a publication of the Society of Behavioral Medicine, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Depression treatment enhances adherence to antiretroviral therapy: a meta-analysis.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2014
    Pooled it
  4. Pooled it
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  12. Mental Health in Women Living With HIV: The Unique and Unmet Needs.Journal of the International Association of Providers of AIDS Care
    Review
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  14. Predictors of medication adherence among HIV-positive women in North America.Journal of obstetric, gynecologic, and neonatal nursing : JOGNN
    Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Dean G CruessDepartment of Psychology, University of Connecticut, Storrs, USA. Dean.Cruess@uconn.edu
Seth C Kalichman
Christine Amaral
Connie Swetzes
Chauncey Cherry
Moira O Kalichman

Funding

HIV Treatment Adherence/Risk Reduction IntegratedR01MH071164 · NIMH · UNIVERSITY OF CONNECTICUT STORRS · PI KALICHMAN, SETH C · 2005 to 2009
$3.0M
NIMH NIH HHS R01 MH071164NIMH NIH HHS R01MH071164
6 · The paper itself

Abstract

backgroundPsychotropic medications are commonly used for depressive symptoms among people living with HIV/AIDS. PURPOSE: We examined the relationships between adherence to psychotropic medications, depressive symptoms, and antiretroviral adherence.

methodsWe assessed depressive symptoms among 324 people living with HIV/AIDS across a 3-month period (70% men; mean age 45 years; 90% African-American). Psychotropic and antiretroviral adherence was assessed using monthly, unannounced telephone pill counts. Multiple-regression and mediation analyses were utilized to examine associations under investigation.

resultsGreater depressive symptoms were associated with lower antiretroviral and psychotropic medication adherence. Greater adherence to psychotropic medications regardless of medication class was positively related to higher antiretroviral adherence. Greater adherence to psychotropic medications also significantly mediated the association between depressive symptoms and antiretroviral adherence.

conclusionsThis study demonstrates the benefits of adherence to psychotropic medications on both depressive symptoms and antiretroviral adherence. Future work examining psychotropic medication adherence on disease outcomes in people living with HIV/AIDS is warranted.

Indexed as

Acquired Immunodeficiency SyndromeAdultAntidepressive AgentsAnti-Retroviral AgentsDepressionFemaleHIV InfectionsHumansMaleMedication AdherenceMental DisordersMiddle AgedAntidepressive AgentsAnti-Retroviral Agents

Identifiers

PMID22076697
PMCPMC4285379

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.