Evidence map›Paper›PMID 22076558›Full record

ReviewNature reviews. Immunology2011

Peptidoglycan recognition proteins: modulators of the microbiome and inflammation.

Julien Royet, Dipika Gupta, Roman Dziarski

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Immunology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 172 papers.

0numbers the graph read from it
0cells of the map it votes in
172citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

172 citing papers in PubMed.

  1. Trial
  2. Review
  3. Article
  4. Review
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. The Gut Microbiota ofMicroorganisms · 2025
    Review
  13. Article
  14. The peptidoglycan ofScience translational medicine · 2025
    Article
  15. Article
  16. The Role of AaPGRP-LB in the Immune Response ofInternational journal of molecular sciences · 2025
    Article
  17. Article
  18. Article
  19. Modelling host-pathogen interactions:Microbiology (Reading, England) · 2025
    Article
  20. Review

112 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Julien RoyetInstitut de Biologie du Développement de Marseille-Luminy, UMR6216 CNRS et Aix-Marseille Universites, Parc Scientifique de Luminy, Marseille, France. julien.royet@univmed.fr
Dipika Gupta
Roman Dziarski

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

All animals, including humans, live in symbiotic association with microorganisms. The immune system accommodates host colonization by the microbiota, maintains microbiota-host homeostasis and defends against pathogens. This Review analyses how one family of antibacterial pattern recognition molecules - the peptidoglycan recognition proteins - has evolved a fascinating variety of mechanisms to control host interactions with mutualistic, commensal and parasitic microorganisms to benefit both invertebrate and vertebrate hosts.

Indexed as

AnimalsAnimal StructuresAntimicrobial Cationic PeptidesCarrier ProteinsConserved SequenceEmbryo, NonmammalianEukaryotaHomeostasisHost-Parasite InteractionsHost-Pathogen InteractionsHumansImmunity, InnateInflammationIntestinesInvertebratesMetagenomeAntimicrobial Cationic PeptidesCarrier ProteinsPeptidoglycanpeptidoglycan recognition protein

Identifiers

PMID22076558

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.