ArticleNucleic acids research2012
OGEE: an online gene essentiality database.
Article in Nucleic acids research, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 90 papers.
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Who cites it
90 citing papers in PubMed, 197 citations in OpenAlex.
- Computational guided identification of novel anti-mycobacterial agent proved by in-vitro and in-vivo validation.BMC microbiology · 2025Article
- Genetic Background and Gene Essentiality.Genes · 2025Article
- Constructing multilayer PPI networks based on homologous proteins and integrating multiple PageRank to identify essential proteins.BMC bioinformatics · 2025Article
- Machine learning methods for predicting essential metabolic genes from Plasmodium falciparum genome-scale metabolic network.PloS one · 2024Article
- A seed expansion-based method to identify essential proteins by integrating protein-protein interaction sub-networks and multiple biological characteristics.BMC bioinformatics · 2023Article
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- merlin, an improved framework for the reconstruction of high-quality genome-scale metabolic models.Nucleic acids research · 2022Article
- In silico Methods for Identification of Potential Therapeutic Targets.Interdisciplinary sciences, computational life sciences · 2022Review
- A Method to Map Gene Essentiality of Human Pluripotent Stem Cells by Genome-Scale CRISPR Screens with Inducible Cas9.Methods in molecular biology (Clifton, N.J.) · 2022Article
- Identifying digenic disease genes via machine learning in the Undiagnosed Diseases Network.American journal of human genetics · 2021Article
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- Identification of Therapeutic Targets for the Selective Killing of HBV-Positive Hepatocytes.Journal of personalized medicine · 2021Article
- On the relation of gene essentiality to intron structure: a computational and deep learning approach.Life science alliance · 2021Article
- Internetwork connectivity of molecular networks across species of life.Scientific reports · 2021Article
- OGEE v3: Online GEne Essentiality database with increased coverage of organisms and human cell lines.Nucleic acids research · 2021Article
- Research on the Computational Prediction of Essential Genes.Frontiers in cell and developmental biology · 2021Review
- DeeplyEssential: a deep neural network for predicting essential genes in microbes.BMC bioinformatics · 2020Article
- Article
- New insights on human essential genes based on integrated analysis and the construction of the HEGIAP web-based platform.Briefings in bioinformatics · 2020Article
30 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
OGEE is an Online GEne Essentiality database. Its main purpose is to enhance our understanding of the essentiality of genes. This is achieved by collecting not only experimentally tested essential and non-essential genes, but also associated gene features such as expression profiles, duplication status, conservation across species, evolutionary origins and involvement in embryonic development. We focus on large-scale experiments and complement our data with text-mining results. Genes are organized into data sets according to their sources. Genes with variable essentiality status across data sets are tagged as conditionally essential, highlighting the complex interplay between gene functions and environments. Linked tools allow the user to compare gene essentiality among different gene groups, or compare features of essential genes to non-essential genes, and visualize the results. OGEE is freely available at http://ogeedb.embl.de.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.