Evidence map›Paper›PMID 22075589›Full record

ArticleJournal of clinical microbiology2012

Clostridium difficile mixed infection and reinfection.

David W Eyre, A Sarah Walker, David Griffiths, Mark H Wilcox, David H Wyllie, Kate E Dingle, Derrick W Crook, Tim E A Peto

Abstract read
In one paragraph

Article in Journal of clinical microbiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed.

  1. Trial
  2. Review
  3. Review
  4. High Prevalence of Genetically RelatedFrontiers in microbiology · 2020
    Article
  5. Article
  6. Article
  7. Recent advances in the treatment ofInfection and drug resistance · 2019
    Article
  8. A Review of Mixed StrainFrontiers in microbiology · 2019
    Review
  9. Article
  10. Article
  11. Article
  12. Role of Coinfecting Strains in Recurrent Clostridium difficile Infection.Infection control and hospital epidemiology · 2016
    Article
  13. Article
  14. Genome-Based Infection Tracking Reveals Dynamics of Clostridium difficile Transmission and Disease Recurrence.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2016
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Clostridium difficile phages: still difficult?Frontiers in microbiology · 2014
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

David W EyreNIHR Oxford Biomedical Research Centre, John Radcliffe Hospital, Oxford, United Kingdom. david.eyre@ndm.ox.ac.uk
A Sarah Walker
David Griffiths
Mark H Wilcox
David H Wyllie
Kate E Dingle
Derrick W Crook
Tim E A Peto

Funding

Department of Health DRF-2010-03-40
6 · The paper itself

Abstract

Isolates from consecutive Clostridium difficile infection (CDI) fecal samples underwent multilocus sequence typing. Potential reinfections with different genotypes were identified in 88/560 (16%) sample pairs taken 1 to 1,414 days (median, 24; interquartile range [IQR], 1 to 52 days) apart; odds of reinfection increased by 58% for every doubling of time between samples. Of 109 sample pairs taken on the same day, 3 (3%) had different genotypes. Considering samples 0 to 7 days apart as the same CDI, 7% of cases had mixed infections with >1 genotype.

Indexed as

Clostridioides difficileClostridium InfectionsCluster AnalysisCoinfectionFecesGenotypeHumansMolecular EpidemiologyMultilocus Sequence TypingRecurrence

Identifiers

PMID22075589
PMCPMC3256686

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.