ArticleJournal of clinical microbiology2012
Delineation of Streptococcus dysgalactiae, its subspecies, and its clinical and phylogenetic relationship to Streptococcus pyogenes.
Article in Journal of clinical microbiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers, 1 of them a synthesis that pooled it.
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Who cites it
52 citing papers in PubMed, 1 synthesis or guideline pooled it, 120 citations in OpenAlex.
- Clinical practice guideline: tonsillitis I. Diagnostics and nonsurgical management.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2016Guideline
- Development of a Colourimetric Loop-Mediated Isothermal Amplification Assay for Rapid Detection of Streptococcus dysgalactiae.Journal of fish diseases · 2026Article
- Dominance of the ST20Microorganisms · 2026Article
- Genomic and patient epidemiology ofMicrobiology spectrum · 2026Article
- Streptococcus dysgalactiae subsp. equisimilis bacteremia in Finland: changes in emm-type distribution combined with clinical presentation.BMC infectious diseases · 2025Article
- Tricuspid valve endocarditis in a horse owner, caused byASM case reports · 2025Article
- Toxic Shock Syndrome Caused by Streptococcus dysgalactiae Subspecies equisimilis: A Report of a Rare Pediatric Case.Cureus · 2025Article
- Genetic analysis reveals the genetic diversity and zoonotic potential of Streptococcus dysgalactiae isolates from sheep.Scientific reports · 2025Article
- Group C Beta Haemolytic Streptococcus Causing Necrotising Pneumonia Complicated With a Pyopneumothorax.Case reports in pulmonology · 2025Article
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- Genetic modification ofmSphere · 2024Article
- Diagnosis of Neurological Involvement Caused byInfection and drug resistance · 2024Article
- Invasive beta-haemolytic streptococcal infections, Finland, 2006 to 2020: increase in Lancefield group C/G infections.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2023Article
- Streptococcus dysgalactiae subsp. dysgalactiae presents with progressive weakness in limbs: a case report and literature review.BMC infectious diseases · 2023Review
- A New Integrative and Mobilizable Element Is a Major Contributor to Tetracycline Resistance inAntibiotics (Basel, Switzerland) · 2023Article
- A Case Report of Streptococcus Dysgalactiae Toxic Shock Syndrome Complicated with Symmetric Peripheral Gangrene.Infection and drug resistance · 2023Article
- Phylogenetic analysis and accessory genome diversity reveal insight into the evolutionary history ofFrontiers in microbiology · 2022Article
- Vaginal microbiota differences associated with pelvic organ prolapse risk during late gestation in commercial sows†.Biology of reproduction · 2021Article
- Whole genome sequencing reveals possible host species adaptation of Streptococcus dysgalactiae.Scientific reports · 2021Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The taxonomic status and structure of Streptococcus dysgalactiae have been the object of much confusion. Bacteria belonging to this species are usually referred to as Lancefield group C or group G streptococci in clinical settings in spite of the fact that these terms lack precision and prevent recognition of the exact clinical relevance of these bacteria. The purpose of this study was to develop an improved basis for delineation and identification of the individual species of the pyogenic group of streptococci in the clinical microbiology laboratory, with a special focus on S. dysgalactiae. We critically reexamined the genetic relationships of the species S. dysgalactiae, Streptococcus pyogenes, Streptococcus canis, and Streptococcus equi, which may share Lancefield group antigens, by phylogenetic reconstruction based on multilocus sequence analysis (MLSA) and 16S rRNA gene sequences and by emm typing combined with phenotypic characterization. Analysis of concatenated sequences of seven genes previously used for examination of viridans streptococci distinguished robust and coherent clusters. S. dysgalactiae consists of two separate clusters consistent with the two recognized subspecies dysgalactiae and equisimilis. Both taxa share alleles with S. pyogenes in several housekeeping genes, which invalidates identification based on single-locus sequencing. S. dysgalactiae, S. canis, and S. pyogenes constitute a closely related branch within the genus Streptococcus indicative of recent descent from a common ancestor, while S. equi is highly divergent from other species of the pyogenic group streptococci. The results provide an improved basis for identification of clinically important pyogenic group streptococci and explain the overlapping spectrum of infections caused by the species associated with humans.
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