Evidence map›Paper›PMID 22075329›Full record

ArticleThe Journal of allergy and clinical immunology2012

Personal and parental nativity as risk factors for food sensitization.

Corinne A Keet, Robert A Wood, Elizabeth C Matsui

Abstract read
In one paragraph

Article in The Journal of allergy and clinical immunology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Demographic characteristics associated with food allergy in a Nationwide Canadian Study.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2021
    Article
  9. Review
  10. Article
  11. Allergic diseases among Asian children in the United States.The Journal of allergy and clinical immunology · 2019
    Article
  12. Review
  13. Mechanisms of gastrointestinal allergic disorders.The Journal of clinical investigation · 2019
    Review
  14. Nativity as a Determinant of Health Disparities Among Children.Journal of immigrant and minority health · 2018
    Article
  15. Childhood food allergies: An evolutionary mismatch hypothesis.Evolution, medicine, and public health · 2017
    Article
  16. Food allergy: epidemiology and natural history.Immunology and allergy clinics of North America · 2015
    Review
  17. Review
  18. Article
  19. Review
  20. Food allergy: temporal trends and determinants.Current allergy and asthma reports · 2012
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Corinne A KeetDivision of Allergy and Immunology, Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Md 21202, USA.
Robert A Wood
Elizabeth C Matsui

Funding

Institute for Clinical and Translational Research (KL2)KL2RR025006 · NCRR · JOHNS HOPKINS UNIVERSITY · PI FORD, DANIEL ERNEST · 2007 to 2011
$12.9M
NCRR NIH HHS 1KL2RR025006-01NCRR NIH HHS KL2 RR025006
6 · The paper itself

Abstract

backgroundImmigrants to developed countries have low rates of aeroallergen sensitization and asthma, but less is known about both food allergy and the role of parental immigration status.

objectiveWe sought to evaluate the relationship between personal and parental nativity and the risk of food sensitization.

methodsThree thousand five hundred fifty subjects less than 21 years old from the Nation Health and Examination Survey 2005-2006 were included. Odds ratios (ORs) were generated by using logistic regression, which adjusted for race/ethnicity, sex, age, and household income and accounted for the complex survey design. Nativity was classified as US-born or foreign-born, and the age of immigration was estimated. Head-of-household nativity was used as a proxy for parental nativity. Food sensitization was defined as at least 1 specific IgE level of 0.35 kU/L or greater to milk, egg, or peanut. Aeroallergen-specific sensitizations and the presence of asthma, allergic rhinitis, or eczema were also assessed.

resultsCompared with those born outside the United States (US), US-born children and adolescents had higher odds of sensitization to any food (OR, 2.05; 95% CI, 1.49-2.83; P < .001). Among the foreign-born group, those who arrived before 2 years of age had higher odds of food sensitization than those who arrived later (OR, 2.68; 95% CI, 1.19-6.08; P = .02). Within the US-born group, in contrast, children of immigrants were at the highest risk (OR, 1.53; 95% CI, 1.05-2.24; P = .02).

conclusionAlthough foreign-born children and adolescents are at lower risk of food sensitization compared with those born in the US, among those born in the US, the children of immigrants are at the highest risk.

Indexed as

AdolescentAllergensChildChild, PreschoolCohort EffectEmigrants and ImmigrantsFemaleFood HypersensitivityHumansMaleRisk FactorsUnited StatesYoung AdultAllergens

Identifiers

PMID22075329
PMCPMC3382052

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.