Evidence map›Paper›PMID 22074925›Full record

ReviewThe Journal of biological chemistry2012

Photoreceptor signaling: supporting vision across a wide range of light intensities.

Vadim Y Arshavsky, Marie E Burns

Open access · hybridAbstract readReview
In one paragraph

Review in The Journal of biological chemistry, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 140 papers.

0numbers the graph read from it
0cells of the map it votes in
140citing papers in PubMed
6.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

140 citing papers in PubMed, 198 citations in OpenAlex.

  1. Article
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  5. Review
  6. The anticonvulsant and mood-stabilizing drug valproic acid attractsbioRxiv : the preprint server for biology · 2025
    Article
  7. Article
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  9. Review
  10. Review
  11. The Structural and Functional Integrity of Rod Photoreceptor Ribbon Synapses Depends on Redundant Actions of Dynamins 1 and 3.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Article
  12. Review
  13. Article
  14. Article
  15. Article
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  17. Article
  18. Article
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80 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Vadim Y ArshavskyDepartments of Ophthalmology and Pharmacology, Duke University, Durham, North Carolina 27710, USA. vadim.arshavsky@duke.edu
Marie E Burns
Duke University Hospital · USUniversity of California, Davis · US

Funding

VISION RESEARCHP30EY005722 · NEI · DUKE UNIVERSITY · PI Vadim Y Arshavsky · 1985 to 2026
$19.3M
Molecular mechanisms of photoreceptor outer segment morphogenesisR01EY012859 · NEI · MASSACHUSETTS EYE AND EAR INFIRMARY · PI ARSHAVSKY, VADIM Y · 2000 to 2022
$10.0M
Deactivation Mechanisms of Rod PhototransductionR01EY014047 · NEI · UNIVERSITY OF CALIFORNIA DAVIS · PI BURNS, MARIE E · 2002 to 2020
$8.5M
Transducin movement and photoreceptor light adaptationR01EY010336 · NEI · UNIVERSITY OF WISCONSIN MADISON · PI ARSHAVSKY, VADIM Y · 1994 to 2012
$6.3M
NEI NIH HHS EY10336NEI NIH HHS EY12859NEI NIH HHS P30 EY005722NEI NIH HHS R01 EY012859NEI NIH HHS R01 EY014047
6 · The paper itself

Abstract

For decades, photoreceptors have been an outstanding model system for elucidating basic principles in sensory transduction and biochemistry and for understanding many facets of neuronal cell biology. In recent years, new knowledge of the kinetics of signaling and the large-scale movements of proteins underlying signaling has led to a deeper appreciation of the photoreceptor's unique challenge in mediating the first steps in vision over a wide range of light intensities.

Indexed as

LightAnimalsHumansPhotoreceptor Cells, VertebrateSignal Transduction

Identifiers

PMID22074925
PMCPMC3265842
OpenAlexW2091521215

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.