Evidence map›Paper›PMID 22074632›Full record

ArticleTransfusion2011

The role of HSAL (SALL) genes in proliferation and differentiation in normal hematopoiesis and leukemogenesis.

Li Chai

Open access · greenAbstract read
In one paragraph

Article in Transfusion, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 24 citations in OpenAlex.

  1. Trial
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  4. Review
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  12. The tumor suppressor protein p150(Sal2) in carcinogenesis.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine · 2015
    Review
  13. Article
  14. Article
  15. Molecular regulation of kidney development.Anatomy & cell biology · 2013
    Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Li ChaiDepartment of Pathology, Joint Program in Transfusion Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA. lchai@partners.org
Brigham and Women's Hospital · US

Funding

Transcription regulation in hematopoiesisP01HL095489 · NHLBI · BOSTON CHILDREN'S HOSPITAL · PI PARK, SHINYOUNG · 2010 to 2020
$20.1M
Hematopoietic stem cell commitmentP01DK080665 · NIDDK · BETH ISRAEL DEACONESS MEDICAL CENTER · PI TENEN, DANIEL G · 2008 to 2012
$7.3M
SELF-RENEWAL IN LEUKEMIC STEM CELLSR01HL092437 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI CHAI, LI · 2008 to 2012
$2.4M
NHLBI NIH HHS P01 HL095489NHLBI NIH HHS P01HL095489NHLBI NIH HHS R01 HL092437NHLBI NIH HHS R01HL092437NHLBI NIH HHS R01HL092437-A1S1NIDDK NIH HHS P01 DK080665NIDDK NIH HHS P01DK080665
6 · The paper itself

Abstract

The National Blood Foundation (NBF) support was critical in the author's research career development. The NBF support came in the form of a start-up seed grant that she got from the American Association of Blood Banks, an organization that advances the practice and standards of transfusion medicine and cellular therapies and an organization in which she is a proud member. The NBF grant enabled her to keep up with her transfusion medicine practice while pursuing her passion to be a physician scientist. During its funding period, she was able to obtain critical preliminary bench data and to secure several National Institutes of Health grants with over a million dollars direct cost. In addition, the knowledge gained from the NBF-supported projects is currently being translated into medical practice in her lab by testing on cord blood expansion. She is looking forward to spending the upcoming years of her professional career bridging bedside observations on transfusion medicine with bench experiences and then utilizing that bench-derived knowledge in the practice of transfusion medicine.

Indexed as

AnimalsCell DivisionCell Transformation, NeoplasticDNA-Binding ProteinsEmbryonic DevelopmentFemaleGenes, p53HematopoiesisHomeodomain ProteinsHumansIntracellular Signaling Peptides and ProteinsLeukemia, Myeloid, AcuteLymphomaMiceMice, KnockoutOvarian NeoplasmsDNA-Binding ProteinsHomeodomain ProteinsIntracellular Signaling Peptides and ProteinsSALL1 protein, humanSall1 protein, mouseSALL2 protein, humanSall2 protein, mouseSALL3 protein, humanSall3 protein, mouseSALL4 protein, humanSall4 protein, mouseTranscription Factors

Identifiers

PMID22074632
PMCPMC3258526
OpenAlexW1939251269

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.