ReviewCurrent topics in developmental biology2011
New insights into signaling during myelination in zebrafish.
Review in Current topics in developmental biology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
19 citing papers in PubMed, 41 citations in OpenAlex.
- Prognostic value and potential upstream regulator of Schwann cells in esophageal squamous cell carcinoma.Translational cancer research · 2026Article
- Hearing loss and vestibular schwannoma: new insights into Schwann cells implication.Cell death & disease · 2023Review
- "Knowing It Before Blocking It," the ABCD of the Peripheral Nerves: Part A (Nerve Anatomy and Physiology).Cureus · 2023Review
- Neurotrophins in the Brain of Teleost Fish: The State of the Art.Advances in experimental medicine and biology · 2021Review
- The prion protein is not required for peripheral nerve de- and remyelination after crush injury.PloS one · 2021Article
- Elmo1 function, linked to Rac1 activity, regulates peripheral neuronal numbers and myelination in zebrafish.Cellular and molecular life sciences : CMLS · 2020Article
- Therapeutic strategies for peripheral nerve injury: decellularized nerve conduits and Schwann cell transplantation.Neural regeneration research · 2019Review
- Schwann Cell Precursors; Multipotent Glial Cells in Embryonic Nerves.Frontiers in molecular neuroscience · 2019Review
- Article
- Schwann cell development, maturation and regeneration: a focus on classic and emerging intracellular signaling pathways.Neural regeneration research · 2017Review
- Imaging MyelinationBrain plasticity (Amsterdam, Netherlands) · 2016Review
- Pharmacological treatment and BBB-targeted genetic therapy for MCT8-dependent hypomyelination in zebrafish.Disease models & mechanisms · 2016Article
- An asymptomatic mutation complicating severe chemotherapy-induced peripheral neuropathy (CIPN): a case for personalised medicine and a zebrafish model of CIPN.NPJ genomic medicine · 2016Article
- New insights on Schwann cell development.Glia · 2015Review
- High-resolution live imaging reveals axon-glia interactions during peripheral nerve injury and repair in zebrafish.Disease models & mechanisms · 2015Article
- Schwann Cells: Development and Role in Nerve Repair.Cold Spring Harbor perspectives in biology · 2015Review
- Review
- Expression of purinergic receptor P2Y4 in Schwann cell following nerve regeneration.International journal of clinical and experimental medicine · 2015Article
- Glial cell development and function in zebrafish.Cold Spring Harbor perspectives in biology · 2014Review
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Myelin is a vertebrate adaptation that allows for the rapid propagation of action potentials along axons. Specialized glial cells-oligodendrocytes in the central nervous system (CNS) and Schwann cells in the peripheral nervous system (PNS)-form myelin by repeatedly wrapping axon segments. Debilitating diseases result from the disruption of myelin, including multiple sclerosis and Charcot-Marie-Tooth peripheral neuropathies. The process of myelination involves extensive communication between glial cells and the associated neurons. The past few years have seen important progress in understanding the molecular basis of the signals that coordinate the development of these fascinating cells. This review highlights recent advances in myelination deriving from studies in the zebrafish model system, with a primary focus on the PNS. While Neuregulin1-ErbB signaling has long been known to play important roles in peripheral myelin development, work in zebrafish has elucidated its roles in Schwann cell migration and radial sorting of axons in vivo. Forward genetic screens in zebrafish have also uncovered new genes required for development of myelinated axons, including gpr126, which encodes a G-protein coupled receptor required for Schwann cells to progress beyond the promyelinating stage. In addition, work in zebrafish uncovered new roles for Schwann cells themselves, including in regulating the boundary between the PNS and CNS and positioning a nerve after its initial outgrowth.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.