Evidence map›Paper›PMID 22073941›Full record

ArticleTransfusion2012

Vasovagal reactions in whole blood donors at three REDS-II blood centers in Brazil.

Thelma T Gonçalez, Ester C Sabino, Karen S Schlumpf, David J Wright, Silvana Leao, Divaldo Sampaio, Pedro L Takecian, Anna B Proietti, Anna B Proitetti, Edward Murphy and 3 more

Erratum issuedOpen access · bronzeAbstract read
In one paragraph

Article in Transfusion, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
7.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 42 citations in OpenAlex.

  1. Article
  2. A Cross-Sectional Study of Blood Donors' Psychological Characteristics over 8 Weeks.Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie · 2022
    Article
  3. Plateletpheresis in the Era of Automation: Optimizing Donor Safety and Product Quality Using Modern Apheresis Instruments.Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion · 2021
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  13. [Not Available].Revista brasileira de hematologia e hemoterapia
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4 · The record

Corrections and comments

  • Erratum issued
    Proitetti, Anna B [corrected to Proietti, Anna B]
5 · Who and what money

Authors and funding

13 authors at 5 institutions in 2 countries.

Thelma T GonçalezBlood Systems Research Institute, 270 Masonic Avenue, San Francisco, CA 94118, USA. tgoncalez@bloodsystems.org
Ester C Sabino
Karen S Schlumpf
David J Wright
Silvana Leao
Divaldo Sampaio
Pedro L Takecian
Anna B Proietti
Anna B Proitetti
Edward Murphy
Michael Busch
Brian Custer
NHLBI Retrovirus Epidemiology Donor Study-II (REDS-II), International Component
Fundação Pró-Sangue Hemocentro de São Paulo · BRUniversidade de Pernambuco · BRBlood Systems Research Institute · USWestat (United States) · USUniversidade de São Paulo · BR

Funding

Health Outcomes in Blood Donors and RecipientsK24HL075036 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MURPHY, EDWARD L · 2004 to 2013
$1.6M
NHLBI NIH HHS HHSN268200417175CNHLBI NIH HHS K24 HL075036
6 · The paper itself

Abstract

backgroundIn Brazil little is known about adverse reactions during donation and the donor characteristics that may be associated with such events. Donors are offered snacks and fluids before donating and are required to consume a light meal after donation. For these reasons the frequency of reactions may be different than those observed in other countries. STUDY DESIGN AND

methodsA cross-sectional study was conducted of eligible whole blood donors at three large blood centers located in Brazil between July 2007 and December 2009. Vasovagal reactions (VVRs) along with donor demographic and biometric data were collected. Reactions were defined as any presyncopal or syncopal event during the donation process. Multivariable logistic regression was performed to identify predictors of VVRs.

resultsOf 724,861 donor presentations, 16,129 (2.2%) VVRs were recorded. Rates varied substantially between the three centers: 53, 290, and 381 per 10,000 donations in Recife, São Paulo, and Belo Horizonte, respectively. Although the reaction rates varied, the donor characteristics associated with VVRs were similar (younger age [18-29 years], replacement donors, first-time donors, low estimated blood volume [EBV]). In multivariable analysis controlling for differences between the donor populations in each city younger age, first-time donor status, and lower EBV were the factors most associated with reactions.

conclusionFactors associated with VVRs in other locations are also evident in Brazil. The difference in VVR rates between the three centers might be due to different procedures for identifying and reporting the reactions. Potential interventions to reduce the risk of reactions in Brazil should be considered.

Indexed as

Blood DonorsAdolescentAdultAgedBrazilCross-Sectional StudiesFemaleHumansLogistic ModelsMaleMiddle AgedSyncope, Vasovagal

Identifiers

PMID22073941
PMCPMC3687805
OpenAlexW2098741907

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.