ArticlePloS one2011
Altered dark- and photoconversion of phytochrome B mediate extreme light sensitivity and loss of photoreversibility of the phyB-401 mutant.
Article in PloS one, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 34 citations in OpenAlex.
- Modulation of warm temperature-sensitive growth using a phytochrome B dark reversion variant, phyB[G515E], in Arabidopsis and rice.Journal of advanced research · 2024Article
- The Arabidopsis endosperm is a temperature-sensing tissue that implements seed thermoinhibition through phyB.Nature communications · 2023Article
- Cannabinoids Accumulation in Hemp (Biology · 2021Article
- High Ambient Temperature Accelerates Leaf Senescence via PHYTOCHROME-INTERACTING FACTOR 4 and 5 inMolecules and cells · 2020Article
- Dark, Light, and Temperature: Key Players in Plant Morphogenesis.Plant physiology · 2019Article
- Phytochrome B1-dependent control of SP5G transcription is the basis of the night break and red to far-red light ratio effects in tomato flowering.BMC plant biology · 2018Article
- Exposure to lower red to far-red light ratios improve tomato tolerance to salt stress.BMC plant biology · 2018Article
- 3D Structures of Plant Phytochrome A as Pr and Pfr From Solid-State NMR: Implications for Molecular Function.Frontiers in plant science · 2018Article
- PCH1 and PCHL promote photomorphogenesis in plants by controlling phytochrome B dark reversion.Nature communications · 2017Article
- Photosensing and Thermosensing by Phytochrome B Require Both Proximal and Distal Allosteric Features within the Dimeric Photoreceptor.Scientific reports · 2017Article
- Phytochromes: an atomic perspective on photoactivation and signaling.The Plant cell · 2014Review
- Arabidopsis cell expansion is controlled by a photothermal switch.Nature communications · 2014Article
- Phytochrome B Nuclear Bodies Respond to the Low Red to Far-Red Ratio and to the Reduced Irradiance of Canopy Shade in Arabidopsis.Plant physiology · 2014Article
- Crystal structure of the photosensing module from a red/far-red light-absorbing plant phytochrome.Proceedings of the National Academy of Sciences of the United States of America · 2014Article
- Engineering adenylate cyclases regulated by near-infrared window light.Proceedings of the National Academy of Sciences of the United States of America · 2014Article
- Photobody Localization of Phytochrome B Is Tightly Correlated with Prolonged and Light-Dependent Inhibition of Hypocotyl Elongation in the Dark.Plant physiology · 2014Article
- Structure-guided engineering of plant phytochrome B with altered photochemistry and light signaling.Plant physiology · 2013Article
- Phosphorylation of phytochrome B inhibits light-induced signaling via accelerated dark reversion in Arabidopsis.The Plant cell · 2013Article
- Intramolecular uncoupling of chromophore photoconversion from structural signaling determinants drive mutant phytochrome B photoreceptor to far-red light perception.Plant signaling & behavior · 2012Article
- Arabidopsis phytochrome a is modularly structured to integrate the multiple features that are required for a highly sensitized phytochrome.The Plant cell · 2012Article
Corrections and comments
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Authors and funding
10 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The phyB-401 mutant is 10(3) fold more sensitive to red light than its wild-type analogue and shows loss of photoreversibility of hypocotyl growth inhibition. The phyB-401 photoreceptor displays normal spectral properties and shows almost no dark reversion when expressed in yeast cells. To gain insight into the molecular mechanism underlying this complex phenotype, we generated transgenic lines expressing the mutant and wild-type phyB in phyB-9 background. Analysis of these transgenic lines demonstrated that the mutant photoreceptor displays a reduced rate of dark-reversion but normal P(fr) to P(r) photoconversion in vivo and shows an altered pattern of association/dissociation with nuclear bodies compared to wild-type phyB. In addition we show (i) an enhanced responsiveness to far-red light for hypocotyl growth inhibition and CAB2 expression and (ii) that far-red light mediated photoreversibility of red light induced responses, including inhibition of hypocotyl growth, formation of nuclear bodies and induction of CAB2 expression is reduced in these transgenic lines. We hypothesize that the incomplete photoreversibility of signalling is due to the fact that far-red light induced photoconversion of the chromophore is at least partially uncoupled from the P(fr) to P(r) conformation change of the protein. It follows that the phyB-401 photoreceptor retains a P(fr)-like structure (P(r) (*)) for a few hours after the far-red light treatment. The greatly reduced rate of dark reversion and the formation of a biologically active P(r) (*) conformer satisfactorily explain the complex phenotype of the phyB-401 mutant and suggest that amino acid residues surrounding the position 564 G play an important role in fine-tuning phyB signalling.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.