ArticlePloS one2011
Transcriptomics responses in marine diatom Thalassiosira pseudonana exposed to the polycyclic aromatic hydrocarbon benzo[a]pyrene.
Article in PloS one, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
20 citing papers in PubMed, 63 citations in OpenAlex.
- Microbial response and resistance mechanisms against diverse anthropogenic pollutants.Frontiers in microbiology · 2026Review
- Heat Shock Protein 104 (Genes · 2025Article
- Holographic tomography of the diatom Skeletonema pseudocostatum used as a bioindicator of heavy metal-polluted waters.PloS one · 2025Article
- LoweringMicroorganisms · 2021Article
- Molecular mechanism of oil induced growth inhibition in diatoms using Thalassiosira pseudonana as the model species.Scientific reports · 2021Article
- Identification of a Metacaspase Gene in the Bloom-Forming Dinoflagellate Prorocentrum minimum and its Putative Function Involved in Programmed Cell Death.Current microbiology · 2021Article
- Influence of nutrient status on the response of the diatom Phaeodactylum tricornutum to oil and dispersant.PloS one · 2021Article
- A Genome-Scale Metabolic Model ofMicroorganisms · 2020Article
- ABC Transporters inMarine drugs · 2019Article
- Article
- Characterization of transcriptional responses mediated by benzo[a]pyrene stress in a new marine fish model of goby, Mugilogobius chulae.Genes & genomics · 2019Article
- Morphological, physiological and molecular responses of Nitzschia palea under cadmium stress.Ecotoxicology (London, England) · 2018Article
- Structural and functional diversity of caspase homologues in non-metazoan organisms.Protoplasma · 2018Review
- The Combination of RNA and Protein Profiling Reveals the Response to Nitrogen Depletion in Thalassiosira pseudonana.Scientific reports · 2017Article
- Marine diatoms change their gene expression profile when exposed to microscale turbulence under nutrient replete conditions.Scientific reports · 2017Article
- Accumulation of petroleum hydrocarbons in intracellular lipid bodies of the freshwater diatom Synedra acus subsp. radians.Environmental science and pollution research international · 2017Article
- Genetic and physiological responses of three freshwater diatoms to realistic diuron exposures.Environmental science and pollution research international · 2015Article
- Transcriptome response to alkane biofuels in Saccharomyces cerevisiae: identification of efflux pumps involved in alkane tolerance.Biotechnology for biofuels · 2013Article
- The central carbon and energy metabolism of marine diatoms.Metabolites · 2013Article
- Genome-wide diel growth state transitions in the diatom Thalassiosira pseudonana.Proceedings of the National Academy of Sciences of the United States of America · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Diatoms are unicellular, photosynthetic, eukaryotic algae with a ubiquitous distribution in water environments and they play an important role in the carbon cycle. Molecular or morphological changes in these species under ecological stress conditions are expected to serve as early indicators of toxicity and can point to a global impact on the entire ecosystem. Thalassiosira pseudonana, a marine diatom and the first with a fully sequenced genome has been selected as an aquatic model organism for ecotoxicological studies using molecular tools. A customized DNA microarray containing probes for the available gene sequences has been developed and tested to analyze the effects of a common pollutant, benzo(a)pyrene (BaP), at a sub-lethal concentration. This approach in diatoms has helped to elucidate pathway/metabolic processes involved in the mode of action of this pollutant, including lipid metabolism, silicon metabolism and stress response. A dose-response of BaP on diatoms has been made and the effect of this compound on the expression of selected genes was assessed by quantitative real time-PCR. Up-regulation of the long-chain acyl-CoA synthetase and the anti-apoptotic transmembrane Bax inhibitor, as well as down-regulation of silicon transporter 1 and a heat shock factor was confirmed at lower concentrations of BaP, but not the heat-shock protein 20. The study has allowed the identification of molecular biomarkers to BaP to be later on integrated into environmental monitoring for water quality assessment.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.