ArticlePloS one2011
Rapid typing of Coxiella burnetii.
Article in PloS one, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
52 citing papers in PubMed, 90 citations in OpenAlex.
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- Longitudinal surveillance ofFrontiers in veterinary science · 2024Article
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- The lower Saint Lawrence River region of Quebec, a hot spot for sheepfold-associated Q fever in Canada: Review of 258 cases.Journal of the Association of Medical Microbiology and Infectious Disease Canada = Journal officiel de l'Association pour la microbiologie medicale et l'infectiologie Canada · 2023Article
- Modulation of the E-cadherin in human cells infected in vitro with Coxiella burnetii.PloS one · 2023Article
- Genotyping ofGenes · 2022Article
- Genetic Diversity ofPathogens (Basel, Switzerland) · 2022Article
- Serological, Molecular Prevalence and Genotyping ofVeterinary sciences · 2022Article
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- The epidemic of Q fever in 2018 to 2019 in Zhuhai city of China determined by metagenomic next-generation sequencing.PLoS neglected tropical diseases · 2021Article
- Correlating Genotyping Data ofPathogens (Basel, Switzerland) · 2021Article
- TheJournal of bacteriology · 2021Article
- In Silico Design of a New Multi-Epitope Peptide-Based Vaccine Candidate Against Q Fever.Molecular biology · 2021Article
- Selective whole genome amplification and sequencing of Coxiella burnetii directly from environmental samples.Genomics · 2020Article
- Phylogeography of Human and AnimalFrontiers in cellular and infection microbiology · 2020Article
- Article
- Comparative virulence of diverse Coxiella burnetii strains.Virulence · 2019Article
- Extensive genome analysis of Coxiella burnetii reveals limited evolution within genomic groups.BMC genomics · 2019Article
- Diagnosis and Genotyping ofOpen forum infectious diseases · 2019Article
- Genotyping of Coxiella burnetii in sheep and goat abortion samples.BMC microbiology · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Coxiella burnetii has the potential to cause serious disease and is highly prevalent in the environment. Despite this, epidemiological data are sparse and isolate collections are typically small, rare, and difficult to share among laboratories as this pathogen is governed by select agent rules and fastidious to culture. With the advent of whole genome sequencing, some of this knowledge gap has been overcome by the development of genotyping schemes, however many of these methods are cumbersome and not readily transferable between institutions. As comparisons of the few existing collections can dramatically increase our knowledge of the evolution and phylogeography of the species, we aimed to facilitate such comparisons by extracting SNP signatures from past genotyping efforts and then incorporated these signatures into assays that quickly and easily define genotypes and phylogenetic groups. We found 91 polymorphisms (SNPs and indels) among multispacer sequence typing (MST) loci and designed 14 SNP-based assays that could be used to type samples based on previously established phylogenetic groups. These assays are rapid, inexpensive, real-time PCR assays whose results are unambiguous. Data from these assays allowed us to assign 43 previously untyped isolates to established genotypes and genomic groups. Furthermore, genotyping results based on assays from the signatures provided here are easily transferred between institutions, readily interpreted phylogenetically and simple to adapt to new genotyping technologies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.