Evidence map›Paper›PMID 22072848›Full record

ReviewWorld journal of gastroenterology2011

Barrett's esophagus with high-grade dysplasia: focus on current treatment options.

Leonidas Lekakos, Nikolaos P Karidis, Dimitrios Dimitroulis, Christos Tsigris, Gregory Kouraklis, Nikolaos Nikiteas

Open access · hybridAbstract readReview
In one paragraph

Review in World journal of gastroenterology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Photodynamic therapy in gastroenterology.Journal of gastrointestinal cancer · 2013
    Review
  12. Quality improvement in gastroenterology clinical practice.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2012
    Review
  13. Management strategies of Barrett's esophagus.World journal of gastroenterology · 2012
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 2 countries.

Leonidas LekakosSecond Propedeutic Department of Surgery, Medical School, University of Athens, General Hospital Laiko, Athens 11527, Greece.
Nikolaos P Karidis
Dimitrios Dimitroulis
Christos Tsigris
Gregory Kouraklis
Nikolaos Nikiteas
Laiko General Hospital of Athens · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

High-grade dysplasia (HGD) in Barrett's esophagus (BE) is the critical step before invasive esophageal adenocarcinoma. Although its natural history remains unclear, an aggressive therapeutic approach is usually indicated. Esophagectomy represents the only treatment able to reliably eradicate the neoplastic epithelium. In healthy patients with reasonable life expectancy, vagal-sparing esophagectomy, with associated low mortality and low early and late postoperative morbidity, is considered the treatment of choice for BE with HGD. Patients unfit for surgery should be managed in a less aggressive manner, using endoscopic ablation or endoscopic mucosal resection of the entire BE segment, followed by lifelong surveillance. Patients eligible for surgery who present with a long BE segment, multifocal dysplastic lesions, severe reflux symptoms, a large fixed hiatal hernia or dysphagia comprise a challenging group with regard to the appropriate treatment, either surgical or endoscopic.

Indexed as

Barrett EsophagusCatheter AblationEsophagectomyEsophagoscopyGastroesophageal RefluxHumansPhotochemotherapyPrecancerous ConditionsBarrett’s esophagusEndoscopic ablationEndoscopic excisionHigh-grade dysplasiaSurgical treatment

Identifiers

PMID22072848
PMCPMC3208361
OpenAlexW2088952976

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.