ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2011
Two distinct modes of forebrain circuit dynamics underlie temporal patterning in the vocalizations of young songbirds.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.
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41 citing papers in PubMed, 73 citations in OpenAlex.
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- Comparative approaches to the neurobiology of avian vocal learning.Current opinion in neurobiology · 2025Review
- Variable and slow-paced neural dynamics in HVC underlie plastic song production in juvenile zebra finches.BMC neuroscience · 2024Article
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- Numerical study of a convective cooling strategy for increasing safe power levels in two-photon brain imaging.Biomedical optics express · 2024Article
- Anterior forebrain pathway in parrots is necessary for producing learned vocalizations with individual signatures.Current biology : CB · 2023Article
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- Songbird mesostriatal dopamine pathways are spatially segregated before the onset of vocal learning.PloS one · 2023Article
- Resurgent NaNature communications · 2021Article
- Plasticity of stereotyped birdsong driven by chronic manipulation of cortical-basal ganglia activity.Current biology : CB · 2021Article
- Actor-critic reinforcement learning in the songbird.Current opinion in neurobiology · 2020Review
- Systematic errors in connectivity inferred from activity in strongly recurrent networks.Nature neuroscience · 2020Article
- Printable microscale interfaces for long-term peripheral nerve mapping and precision control.Nature communications · 2020Article
- Functional imaging of visual cortical layers and subplate in awake mice with optimized three-photon microscopy.Nature communications · 2019Article
- Vocal learning in songbirds requires cholinergic signaling in a motor cortex-like nucleus.Journal of neurophysiology · 2018Article
- Building a state space for song learning.Current opinion in neurobiology · 2018Review
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- Songbirds work around computational complexity by learning song vocabulary independently of sequence.Nature communications · 2017Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
Accurate timing is a critical aspect of motor control, yet the temporal structure of many mature behaviors emerges during learning from highly variable exploratory actions. How does a developing brain acquire the precise control of timing in behavioral sequences? To investigate the development of timing, we analyzed the songs of young juvenile zebra finches. These highly variable vocalizations, akin to human babbling, gradually develop into temporally stereotyped adult songs. We find that the durations of syllables and silences in juvenile singing are formed by a mixture of two distinct modes of timing: a random mode producing broadly distributed durations early in development, and a stereotyped mode underlying the gradual emergence of stereotyped durations. Using lesions, inactivations, and localized brain cooling, we investigated the roles of neural dynamics within two premotor cortical areas in the production of these temporal modes. We find that LMAN (lateral magnocellular nucleus of the nidopallium) is required specifically for the generation of the random mode of timing and that mild cooling of LMAN causes an increase in the durations produced by this mode. On the contrary, HVC (used as a proper name) is required specifically for producing the stereotyped mode of timing, and its cooling causes a slowing of all stereotyped components. These results show that two neural pathways contribute to the timing of juvenile songs and suggest an interesting organization in the forebrain, whereby different brain areas are specialized for the production of distinct forms of neural dynamics.
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