Evidence map›Paper›PMID 22070469›Full record

Trial reportCNS neuroscience & therapeutics2012

Mindfulness-based cognitive therapy for nonremitted patients with bipolar disorder.

Thilo Deckersbach, Britta K Hölzel, Lori R Eisner, Jonathan P Stange, Andrew D Peckham, Darin D Dougherty, Scott L Rauch, Sara Lazar, Andrew A Nierenberg

Abstract readClinical Trial
In one paragraph

Trial report in CNS neuroscience & therapeutics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Mindfulness-based cognitive therapyPsychological medicine · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Thilo DeckersbachDepartment of Psychiatry, Massachusetts General Hospital, Boston, MA 02114, USA. tdeckersbach@partners.org
Britta K Hölzel
Lori R Eisner
Jonathan P Stange
Andrew D Peckham
Darin D Dougherty
Scott L Rauch
Sara Lazar
Andrew A Nierenberg

Funding

Structural, Functional, and Behavioral Effects of MeditationR01AT006344 · NCCIH · MASSACHUSETTS GENERAL HOSPITAL · PI LAZAR, SARA W · 2011 to 2015
$2.2M
Cognitive-Behavior Therapy for Bipolar DisorderK23MH074895 · NIMH · MASSACHUSETTS GENERAL HOSPITAL · PI DECKERSBACH, THILO · 2007 to 2011
$973k
Exploratory Analysis of RR and MBSR for Stress ReductionR21AT003425 · NCCIH · MASSACHUSETTS GENERAL HOSPITAL · PI LAZAR, SARA W · 2007 to 2008
$896k
NCCIH NIH HHS R01 AT006344NCCIH NIH HHS R21 AT003425NIMH NIH HHS 1K23MH074895NIMH NIH HHS K23 MH074895
6 · The paper itself

Abstract

introductionBipolar disorder is characterized by recurrent episodes of depression and/or mania along with interepisodic mood symptoms that interfere with psychosocial functioning. Despite periods of symptomatic recovery, many individuals with bipolar disorder continue to experience substantial residual mood symptoms that often lead to the recurrence of mood episodes.

aimsThis study explored whether a new mindfulness-based cognitive therapy (MBCT) for bipolar disorder would increase mindfulness, reduce residual mood symptoms, and increase emotion-regulation abilities, psychological well-being, positive affect, and psychosocial functioning. Following a baseline clinical assessment, 12 individuals with DSM-IV bipolar disorder were treated with 12 group sessions of MBCT.

resultsAt the end of treatment, as well as at the 3 months follow-up, participants showed increased mindfulness, lower residual depressive mood symptoms, less attentional difficulties, and increased emotion-regulation abilities, psychological well-being, positive affect, and psychosocial functioning.

conclusionsThese findings suggest that treating residual mood symptoms with MBCT may be another avenue to improving mood, emotion regulation, well-being, and functioning in individuals with bipolar disorder.

Indexed as

AdultBipolar DisorderCognitive Behavioral TherapyFemaleHumansMaleMeditationMiddle AgedTreatment Outcome

Identifiers

PMID22070469
PMCPMC3738005

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.