Evidence map›Paper›PMID 22069737›Full record

ArticleToxins2011

Gene expression profiling and identification of resistance genes to Aspergillus flavus infection in peanut through EST and microarray strategies.

Baozhu Guo, Natalie D Fedorova, Xiaoping Chen, Chun-Hua Wan, Wei Wang, William C Nierman, Deepak Bhatnagar, Jiujiang Yu

Open access · goldAbstract read
In one paragraph

Article in Toxins, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
8.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 103 citations in OpenAlex.

  1. Review
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  3. The genusFrontiers in plant science · 2023
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  15. Identification of candidate resistance genes of cotton againstPhysiology and molecular biology of plants : an international journal of functional plant biology · 2018
    Article
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  17. Article
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  19. Expression Profiling Coupled withFrontiers in plant science · 2017
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Baozhu GuoCrop Protection and Management Research Unit, U.S. Department of Agriculture-Agricultural Research Service, Tifton, GA, USA. Baozhu.guo@ars.usda.gov
Natalie D Fedorova
Xiaoping Chen
Chun-Hua Wan
Wei Wang
William C Nierman
Deepak Bhatnagar
Jiujiang Yu
J. Craig Venter Institute · USAgricultural Research Service · USGeorge Washington University · USUnited States Department of Agriculture · USUniversity of Georgia · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aspergillus flavus and A. parasiticus infect peanut seeds and produce aflatoxins, which are associated with various diseases in domestic animals and humans throughout the world. The most cost-effective strategy to minimize aflatoxin contamination involves the development of peanut cultivars that are resistant to fungal infection and/or aflatoxin production. To identify peanut Aspergillus-interactive and peanut Aspergillus-resistance genes, we carried out a large scale peanut Expressed Sequence Tag (EST) project which we used to construct a peanut glass slide oligonucleotide microarray. The fabricated microarray represents over 40% of the protein coding genes in the peanut genome. For expression profiling, resistant and susceptible peanut cultivars were infected with a mixture of Aspergillusflavus and parasiticus spores. The subsequent microarray analysis identified 62 genes in resistant cultivars that were up-expressed in response to Aspergillus infection. In addition, we identified 22 putative Aspergillus-resistance genes that were constitutively up-expressed in the resistant cultivar in comparison to the susceptible cultivar. Some of these genes were homologous to peanut, corn, and soybean genes that were previously shown to confer resistance to fungal infection. This study is a first step towards a comprehensive genome-scale platform for developing Aspergillus-resistant peanut cultivars through targeted marker-assisted breeding and genetic engineering.

Indexed as

Expressed Sequence TagsGene Expression ProfilingArachisAspergillus flavusGenes, FungalGenetic MarkersHost-Pathogen InteractionsOligonucleotide Array Sequence AnalysisPlant DiseasesPlant ImmunitySequence Analysis, DNAGenetic MarkersA. parasiticusAspergillus flavusESTgene profilingmetarepmicroarraypeanut-fungus interactionresistance genes

Identifiers

PMID22069737
PMCPMC3202856
OpenAlexW2124890608

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.