Evidence map›Paper›PMID 22069728›Full record

ReviewToxins2011

Shiga toxin: expression, distribution, and its role in the environment.

Steven A Mauro, Gerald B Koudelka

Open access · goldAbstract readReview
In one paragraph

Review in Toxins, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 93 citations in OpenAlex.

  1. Global expression profile of enterohemorrhagic Escherichia coli O157:H7 in phagosome of murine macrophages.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2026
    Article
  2. Article
  3. Inhibition of Shiga Toxin 2 forCurrent medicinal chemistry · 2026
    Article
  4. Article
  5. Inhibition ofMicroorganisms · 2025
    Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. The diverse landscape of AB5-type toxins.Engineering microbiology · 2023
    Review
  11. Review
  12. Recent Advancements in Technologies to Detect EnterohaemorrhagicJournal of microbiology and biotechnology · 2023
    Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Virulence Factors of Enteric PathogenicInternational journal of molecular sciences · 2021
    Review
  18. Article
  19. Nonfimbrial Adhesin Mutants Reveal DivergentInternational journal of microbiology · 2021
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Steven A MauroDepartment of Biological Sciences, Mercyhurst College, Erie, PA 16546, USA. smauro@mercyhurst.edu
Gerald B Koudelka
Mercyhurst University · USUniversity at Buffalo, State University of New York · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this review, we highlight recent work that has increased our understanding of the production and distribution of Shiga toxin in the environment. Specifically, we review studies that offer an expanded view of environmental reservoirs for Shiga toxin producing microbes in terrestrial and aquatic ecosystems. We then relate the abundance of Shiga toxin in the environment to work that demonstrates that the genetic mechanisms underlying the production of Shiga toxin genes are modified and embellished beyond the classical microbial gene regulatory paradigms in a manner that apparently "fine tunes" the trigger to modulate the amount of toxin produced. Last, we highlight several recent studies examining microbe/protist interactions that postulate an answer to the outstanding question of why microbes might harbor and express Shiga toxin genes in the environment.

Indexed as

Shiga Toxin 1Shiga Toxin 2BacteriophagesEcosystemEnvironmental MicrobiologyEscherichia coli InfectionsEscherichia coli O157Host-Pathogen InteractionsVirulence FactorsShiga Toxin 1Shiga Toxin 2Virulence FactorsbacteriophageE.coli O157Shiga toxin

Identifiers

PMID22069728
PMCPMC3202840
OpenAlexW1966789105

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.