Evidence map›Paper›PMID 22069604›Full record

ArticleToxins2010

Studies on carcinogenic and toxic effects of ochratoxin A in chicks.

Stoycho D Stoev

Open access · goldAbstract read
In one paragraph

Article in Toxins, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
7.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 79 citations in OpenAlex.

  1. Review
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  5. Article
  6. Review
  7. Risks for animal health related to the presence of ochratoxin A (OTA) in feed.EFSA journal. European Food Safety Authority · 2023
    Article
  8. Review
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  12. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Stoycho D StoevDepartment of General and Clinical Pathology, Faculty of Veterinary Medicine, Trakia University, Students campus, 6000 Stara Zagora, Bulgaria. stoev@uni-sz.bg
Trakia University · BG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Carcinogenic/toxic effects of ochratoxin A (OTA) in various internal organs of Plymouth Rock chicks were determined. The number of OTA-induced neoplasms was similar in chicks given 25 ppm L-β-phenylalanine (PHE) in addition to 5 ppm OTA compared to chicks given only 5 ppm OTA, which showed that PHE cannot be used as a real protector against the carcinogenic or toxic effects of OTA in chicks. OTA was found to provoke strong degenerative changes in liver and kidneys, degenerative changes and depletion of cells in lymphoid organs, oedematous and degenerative changes in the brain, muscular haemorrhages and fatty changes in the bone marrow. The target organs for carcinogenic effect of OTA in chicks were found to be kidneys and liver.

Indexed as

AnimalsChickensFemaleKidneyKidney NeoplasmsLiverLiver Neoplasms, ExperimentalMaleMycotoxinsNeoplasms, ExperimentalOchratoxinsMycotoxinsochratoxin AOchratoxinscarcinogenic effectchicksochratoxin Apathologyphenylalanine

Identifiers

PMID22069604
PMCPMC3153202
OpenAlexW2042454480

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.