ReviewToxins2010
Structure and function of snake venom proteins affecting platelet plug formation.
Review in Toxins, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed, 22 citations in OpenAlex.
- Clinical features of puff adder envenoming: case series of Bitis arietans snakebites in Kenya and a scoping review of the literature.PLoS neglected tropical diseases · 2025Article
- Thromboinflammatory complications ofFrontiers in immunology · 2025Review
- Increased Binding of von Willebrand Factor to Sub-Endothelial Collagen May Facilitate Thrombotic Events ComplicatingToxins · 2023Article
- Bitiscetin-3, a Novel C-Type Lectin-like Protein Cloned from the Venom Gland of the ViperToxins · 2022Article
- SARS-CoV-2 Spike Protein Unlikely to Bind to IntegrinsFrontiers in molecular biosciences · 2022Article
- Coagulopathy After Viper Snakebite in Vietnam and Relationship with Time of Admission.Journal of multidisciplinary healthcare · 2021Article
- Inflammation Induced by Platelet-Activating Viperid Snake Venoms: Perspectives on Thromboinflammation.Frontiers in immunology · 2019Review
- The effect of physiological levels of South African puff adder (Bitis arietans) snake venom on blood cells: an in vitro model.Scientific reports · 2016Article
- At the Frontier; RXLR Effectors Crossing the Phytophthora-Host Interface.Frontiers in plant science · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Many snake venom proteins have been isolated that affect platelet plug formation by interacting either with platelet integrins, membrane glycoprotein Ib (GPIb), or plasma von Willebrand factor (VWF). Among them, disintegrins purified from various snake venoms are strong inhibitors of platelet aggregation. Botrocetin and bitiscetin derived from Bothrops jararaca and Bitis arietans venom, respectively, induce VWF-dependent platelet agglutination in vitro. Several GPIb-binding proteins have also been isolated from snake venoms. In this review, we focus on the structure and function of those snake venom proteins that influence platelet plug formation. These proteins are potentially useful as reagents for the sub-diagnosis of platelet disorder or von Willebrand disease, as well as for clinical and basic research of thrombosis and hemostasis.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.