ReviewToxins2009
Cyclopiazonic acid biosynthesis of Aspergillus flavus and Aspergillus oryzae.
Review in Toxins, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
50 citing papers in PubMed, 138 citations in OpenAlex.
- Characterization of Phenolic Compounds in Almond Skin Extracts by UPLC-TripleTOF-MS/MS and Their Protective Effects Against Cyclopiazonic Acid-Induced Toxicity in SH-SY5Y Cells.Foods (Basel, Switzerland) · 2026Article
- A Single Flavoenzyme Forges the Pentacyclic Skeleton of α-Cyclopiazonic Acid.Journal of the American Chemical Society · 2026Article
- Volatilized Metabolites Produced by Soilborne Aspergillus flavus Regulate Fungal Conidiation, and Production of Secondary Metabolites.Journal of chemical ecology · 2026Article
- Determination of cyclopiazonic acid in food samples by using molecularly imprinted polymers based on magnetic halloysite nanotubes.Analytical and bioanalytical chemistry · 2025Article
- Genome diversity, population structure and MALDI-TOF MS profiling of Aspergillus oryzae/flavus strains from fermentation and wild environments.BMC genomics · 2025Article
- Mycotoxin-free Aspergillus oryzae strain lineage for alternative and novel protein production at industrial scale.Applied microbiology and biotechnology · 2025Review
- In vitro assessment of emerging mycotoxins co-occurring in cheese: a potential health hazard.Archives of toxicology · 2024Article
- The Presence of Some MinorMolecules (Basel, Switzerland) · 2024Article
- The Application of Fungi and Their Secondary Metabolites in Aquaculture.Journal of fungi (Basel, Switzerland) · 2024Review
- Comparative analysis of the genomes and aflatoxin production patterns of three species within the Aspergillus section Flavi reveals an undescribed chemotype and habitat-specific genetic traits.Communications biology · 2024Article
- Maize Aspergillus section Flavi isolate diversity may be distinct from that of soil and subsequently the source of aflatoxin contamination.Mycotoxin research · 2024Article
- The Near-GaplessJournal of fungi (Basel, Switzerland) · 2024Article
- Origin of the 6/5/6/5 Tetracyclic Cyclopiazonic Acids.Marine drugs · 2024Article
- Identification of Virulence Factors in EntomopathogenicMicroorganisms · 2023Article
- Hazard characterisation for significant mycotoxins in food.Mycotoxin research · 2023Review
- RNA-Seq Based Transcriptome Analysis ofJournal of fungi (Basel, Switzerland) · 2022Article
- 'Kodo poisoning': cause, science and management.Journal of food science and technology · 2022Review
- The Solvent Dimethyl Sulfoxide Affects Physiology, Transcriptome and Secondary Metabolism ofJournal of fungi (Basel, Switzerland) · 2021Article
- Distribution ofToxins · 2021Review
- Biosynthetic Cyclization Catalysts for the Assembly of Peptide and Polyketide Natural Products.ChemCatChem · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cyclopiazonic acid (CPA) is an indole-tetramic acid neurotoxin produced by some of the same strains of A. flavus that produce aflatoxins and by some Aspergillus oryzae strains. Despite its discovery 40 years ago, few reviews of its toxicity and biosynthesis have been reported. This review examines what is currently known about the toxicity of CPA to animals and humans, both by itself or in combination with other mycotoxins. The review also discusses CPA biosynthesis and the genetic diversity of CPA production in A. flavus/oryzae populations.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.