ArticlePloS one2011
Does speciation between Arabidopsis halleri and Arabidopsis lyrata coincide with major changes in a molecular target of adaptation?
Article in PloS one, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.
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40 citing papers in PubMed, 103 citations in OpenAlex.
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- Population Genomics Reveals Demographic History and Climate Adaptation in Japanese Arabidopsis halleri.Plant & cell physiology · 2025Article
- Subtle Introgression Footprints at the End of the Speciation Continuum in a Clade of Heliconius Butterflies.Molecular biology and evolution · 2023Article
- The Complex History of Genome Duplication and Hybridization in North American Gray Treefrogs.Molecular biology and evolution · 2022Article
- Low-molecular-weight ligands in plants: role in metal homeostasis and hyperaccumulation.Photosynthesis research · 2021Review
- Demographic Processes Linked to Genetic Diversity and Positive Selection across a Species' Range.Plant communications · 2020Article
- Evolution of self-incompatibility in the Brassicaceae: Lessons from a textbook example of natural selection.Evolutionary applications · 2020Article
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- Diversifying Evolution of the Ubiquitin-26S Proteasome System in Brassicaceae and Poaceae.International journal of molecular sciences · 2019Article
- Combining population genomics and forward simulations to investigate stocking impacts: A case study of Muskellunge (Evolutionary applications · 2019Article
- Bulk pollen sequencing reveals rapid evolution of segregation distortion in the male germline of Arabidopsis hybrids.Evolution letters · 2019Article
- Differential retention of transposable element-derived sequences in outcrossing Arabidopsis genomes.Mobile DNA · 2019Article
- Patterns of polymorphism and selection in the subgenomes of the allopolyploid Arabidopsis kamchatica.Nature communications · 2018Article
- Article
- Article
- Back to America: tracking the origin of European introduced populations of Quercus rubra L.Genome · 2017Article
- Chloroplast genomes of Arabidopsis halleri ssp. gemmifera and Arabidopsis lyrata ssp. petraea: Structures and comparative analysis.Scientific reports · 2017Article
- Evidence for Adaptive Introgression of Disease Resistance Genes Among Closely RelatedG3 (Bethesda, Md.) · 2017Article
- Extensive recent secondary contacts between four European white oak species.The New phytologist · 2017Article
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Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Ever since Darwin proposed natural selection as the driving force for the origin of species, the role of adaptive processes in speciation has remained controversial. In particular, a largely unsolved issue is whether key divergent ecological adaptations are associated with speciation events or evolve secondarily within sister species after the split. The plant Arabidopsis halleri is one of the few species able to colonize soils highly enriched in zinc and cadmium. Recent advances in the molecular genetics of adaptation show that the physiology of this derived ecological trait involves copy number expansions of the AhHMA4 gene, for which orthologs are found in single copy in the closely related A. lyrata and the outgroup A. thaliana. To gain insight into the speciation process, we ask whether adaptive molecular changes at this candidate gene were contemporary with important stages of the speciation process. We first inferred the scenario and timescale of speciation by comparing patterns of variation across the genomic backgrounds of A. halleri and A. lyrata. Then, we estimated the timing of the first duplication of AhHMA4 in A. halleri. Our analysis suggests that the historical split between the two species closely coincides with major changes in this molecular target of adaptation in the A. halleri lineage. These results clearly indicate that these changes evolved in A. halleri well before industrial activities fostered the spread of Zn- and Cd-polluted areas, and suggest that adaptive processes related to heavy-metal homeostasis played a major role in the speciation process.
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